| Type | Description |
|---|---|
| Definition | phospholipase A2, group III |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 12:40:00 | Here the authors have found that sPLA2-III-null (Pla2g3 (-/-)) mice are highly resistant to colon carcinogenesis. Furthermore, Pla2g3 (-/-) mice are less susceptible to dextran sulfate-induced colitis, implying that the amelioration of colonic inflammation by sPLA2-III ablation may underlie the protective effect against colon cancer. | 28947740 |
| 2016-07-02 10:26:00 | Findings show a key role of Pla2g3 on the reduction of IDE, and suggest that cerebrum specific increase of Pla2g3 is involved in the initiation and/or progression of Alzheimer disease. | 26637123 |
| 2013-07-27 11:10:00 | Data indicate a PLA2G3-lipocalin-type PGD2 synthase (L-PGDS)-PGD2 receptor DP1 loop that drives mast cell maturation. | 23624557 |
| 2010-05-31 11:24:00 | the atypical sPLA2 family member sPLA2-III has a role in epididymal lipid homeostasis and its perturbation may lead to sperm dysfunction | 20424323 |
| 2010-01-21 00:00:00 | This study showed that endogenous group III sPLA2 (PLA2G3) is expressed in mouse skin and that transgenic mice overexpressing human PLA2G3 spontaneously develop skin inflammation. | 19371233 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PA2G3_MOUSE,
Q6AXH0_MOUSE
UniprotKB:
Q8BZT7,
Q6AXH0
UniParc:
UPI00000EA3AF,
UPI0000402840
EMBL:
AL713875,
BC079556,
AK033572
Ensembl:
ENSMUSG00000034579
KO:
mmu:237625
|
| Nucleutide sequences |
EMBL-CDS:
BAC28367.1,
AAH79556.1
Ensembl_TRS:
ENSMUST00000064265
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000068699
RefSeq:
XP_036012545.1,
XP_036012542.1,
XP_030101817.1,
XP_036012543.1,
NP_766379.2,
XP_036012544.1,
XP_006514754.1,
XP_006514753.1,
XP_006514752.1
|
| Others |
UniRef100:
UniRef100_Q6AXH0,
UniRef100_Q8BZT7
UniRef90:
UniRef90_Q8BZT7
UniRef50:
UniRef50_Q8BZT7
UniGene:
Mm.100476
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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