| Type | Description |
|---|---|
| Definition | stromal cell derived factor 2 like 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:16:00 | Expression profiles of PRKG1, SDF2L1 and PPP1R12A are predictive and prognostic factors for therapy response and survival in high-grade serous ovarian cancer. | 32096871 |
| 2020-07-18 11:31:00 | The ERdj3-SDF2L1 complex suppressed ER protein aggregation, and this suppression did not require substrate transfer to BiP. | 31624144 |
| 2019-04-13 10:38:00 | In diabetic patients, insufficient induction of Sdf2l1 correlates with progression of insulin resistance and steatohepatitis. Therefore, failure to build an ER stress response in the liver may be a causal factor in obesity-related diabetes and nonalcoholic steatohepatitis, for which Sdf2l1 could serve as a therapeutic target and sensitive biomarker. | 30814508 |
| 2018-01-20 11:10:00 | SDF2L1 associates with ERdj3 and acts as a component in the BiP chaperone cycle to prevent the aggregation of misfolded proteins. | 28597544 |
| 2013-11-02 10:25:00 | SDF2L1 increases the time that misfolded proteins have to achieve a correctly folded conformation and thus that SDF2L1 can act as a buffer for substrate availability for ERAD in pancreatic beta-cells. | 23444373 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SDF2L_HUMAN
UniprotKB:
Q9HCN8
UniParc:
UPI0000048F31
EMBL:
AB043007,
BC132849,
BC132851,
AF277316,
BC006248,
CH471095,
AY359118,
CR456570
Ensembl:
ENSG00000128228
KO:
hsa:23753
|
| Nucleutide sequences |
EMBL-CDS:
AAI32850.1,
EAW59467.1,
BAB18277.1,
AAK69113.1,
AAI32852.1,
AAQ89476.1,
CAG30456.1
Gene_ORFName:
UNQ1941/PRO4424
Ensembl_TRS:
ENST00000248958
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000248958
RefSeq:
NP_071327.2
|
| Others |
UniRef100:
UniRef100_Q9HCN8
UniRef90:
UniRef90_Q9HCN8
UniRef50:
UniRef50_Q9HCN8
UniGene:
Hs.303116
CCDS:
CCDS13792.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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