| Type | Description |
|---|---|
| Definition | OFD1, centriole and centriolar satellite protein |
| Date | Results | Publications |
|---|---|---|
| 2014-06-21 13:07:00 | loss of BBS1, BBS4, or OFD1 led to decreased NF-kappaB activity and concomitant IkappaBbeta accumulation and that these defects were ameliorated with SFN treatment. | 24691443 |
| 2013-12-14 11:26:00 | removal of OFD1 by autophagy at centriolar satellites represents a general mechanism to promote ciliogenesis in mammalian cells | 24089205 |
| 2013-06-29 12:03:00 | the present study identifies Ofd1 as a developmental disease gene that is critical for forebrain development and ciliogenesis in embryonic life, and indicates that Ofd1 functions after docking and before elaboration of the axoneme in vivo. | 23300826 |
| 2011-09-17 11:58:00 | The ciliogenic protein Oral-Facial-Digital 1 regulates the neuronal differentiation of embryonic stem cells. | 20873986 |
| 2011-02-26 10:37:00 | Ofd1 plays a role in regulating digit number and identity during limb and skeletal patterning. | 20920500 |
| Type | IDs |
|---|---|
| Synonymous | Cxorf5, DXGgc7e, ORF2 |
| Gene |
UniProtKB-ID:
OFD1_MOUSE,
A2AEG2_MOUSE,
Q3URP3_MOUSE
UniprotKB:
Q80Z25,
A2AEG2,
Q3URP3
UniParc:
UPI000000D087,
UPI000056511A,
UPI00005AC05E
EMBL:
AJ438159,
BC119070,
AL672174,
BC120487,
AL671905,
AK141310
Ensembl:
ENSMUSG00000040586
KO:
mmu:237222
|
| Nucleutide sequences |
EMBL-CDS:
CAD27225.1,
AAI20488.1,
AAI19071.1,
BAE24645.1
Ensembl_TRS:
ENSMUST00000049501
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041744
RefSeq:
XP_036017840.1,
XP_006528902.1,
NP_803178.2,
XP_036017839.1
|
| Others |
UniRef100:
UniRef100_Q80Z25
UniRef90:
UniRef90_Q80Z25
UniRef50:
UniRef50_Q80Z25
UniGene:
Mm.247480
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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