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237213 Glra2

237213

Glra2

glycine receptor, alpha 2 subunit

protein-coding

Mus musculus

基因描述

Type Description
Definition glycine receptor, alpha 2 subunit

研究结论

Date Results Publications
2020-07-18 12:38:00 T258F gain of function mutation in cerebellar granule cells modifies single-cell and neural network signaling. 30875431
2018-07-28 10:56:00 alpha2 and alpha3 GlyRs are present in various regions of the forebrain and that alpha3 GlyRs specifically participate in tonic inhibition in the striatum and prefrontal cortex. 28784756
2018-02-03 10:11:00 These results, which reveal neurodevelopmental roles for alpha2-GlyRs in the adult brain, may be clinically relevant, given that a mutation in GLAR2, as well as Adult hippocampal neurogenesis impairments. 29057625
2017-05-06 16:56:00 Findings show that the loss of embryonic GlyRalpha2 ultimately impairs the formation of cortical circuits in the mature brain; results demonstrate a physiological role for alpha2 GlyRs during cortical network formation and homeostasis 26891984
2015-06-27 13:40:00 genetic inactivation of Glra2, the gene coding the alpha2 subunit of GlyRs, disrupts dorsal cortical progenitor homeostasis with an impaired capability of apical progenitors to generate basal progenitors. 24926615

名称对应

Type IDs
Gene
UniProtKB-ID: GLRA2_MOUSE, Q3UTL8_MOUSE
UniprotKB: Q7TNC8, Q3UTL8
UniParc: UPI0000195979
EMBL: AK139335, BC056342, BC068987
Ensembl: ENSMUSG00000018589
KO: mmu:237213
Nucleutide sequences
EMBL-CDS: AAH68987.1, AAH56342.1, BAE23962.1
Ensembl_TRS: ENSMUST00000058787
Protein sequencees
Ensembl_PRO: ENSMUSP00000060827
RefSeq: NP_906272.1, XP_036017837.1, XP_006528897.1, XP_006528899.1, XP_030107196.1, NP_001344029.1, NP_001344028.1
Others
UniRef100: UniRef100_Q7TNC8
UniRef90: UniRef90_P23416
UniRef50: UniRef50_P23416
UniGene: Mm.113877
CCDS: CCDS41206.1

全选

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研究热度

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