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237175 Adgrg2

237175

Adgrg2

adhesion G protein-coupled receptor G2

protein-coding

Mus musculus

基因描述

Type Description
Definition adhesion G protein-coupled receptor G2

研究结论

Date Results Publications
2019-08-10 12:34:00 The authors demonstrated that the ubiquitous G protein-coupled receptor signaling proteins Gq and beta-arrestin-1 are essential for fluid reabsorption because they mediate coupling between an orphan receptor ADGRG2 (GPR64) and the ion channel CFTR. 29393851
2019-01-19 10:47:00 Study identified Gpr64 as a P4-PGR target gene in the mouse uterus. P4 induced GPR64 expression in the epithelial and stromal cells of the uterus in ovariectomized wild-type mice, but not in PRKO mice. ChIP analysis confirmed that PGR proteins were recruited on progesterone response element of Gpr64 gene in the uteri of wild-type mice treated with P4. 28694502
2015-11-14 11:29:00 examined the G protein-coupling abilities of GPR64 and showed that it is activated through a tethered agonist sequence, which we have previously identified as the Stachel sequence 26188515
2013-06-15 12:06:00 GPR64 expression in ES maintains an immature phenotype that is less sensitive to TRAIL-induced apoptosis and via its up-regulation of PGF and MMP1 orchestrates and promotes invasiveness and metastatic spread in Ewing sarcoma. 23338946
2010-01-21 00:00:00 The knockout of the HE6/Gpr64 receptor was mainly associated with the downregulation of genes specific to the initial segment. 17034053

名称对应

Type IDs
Synonymous AW212196, B830041D06Rik, Gpr64, Me6
Gene
UniProtKB-ID: AGRG2_MOUSE, Q14BH6_MOUSE, Q14AX7_MOUSE
UniprotKB: Q8CJ12, Q14BH6, Q14AX7
UniParc: UPI00000E8BD3, UPI0000193230, UPI00000E8BD2, UPI000034E5C0, UPI00000E8BD4, UPI00000E8BD0
EMBL: AK046871, AF538956, AF538952, AL731801, BC115874, BC116644, AF538955, AF538957
Ensembl: ENSMUSG00000031298
KO: mmu:237175
Nucleutide sequences
EMBL-CDS: AAN33059.1, AAN33054.1, AAN33057.1, AAN33058.1, BAC32902.1, AAI15875.1, AAI16645.1
Ensembl_TRS: ENSMUST00000112402, ENSMUST00000112404, ENSMUST00000112408, ENSMUST00000112400, ENSMUST00000112405, ENSMUST00000112401
Protein sequencees
Ensembl_PRO: ENSMUSP00000108027, ENSMUSP00000108024, ENSMUSP00000108021, ENSMUSP00000108023, ENSMUSP00000108019, ENSMUSP00000108020
RefSeq: XP_036017835.1, XP_036017830.1, XP_006528879.1, XP_036017836.1, XP_006528876.1, NP_001277374.1, NP_848827.1, XP_006528872.1, XP_006528870.1, NP_001073316.1, XP_011246119.1, XP_006528890.1, NP_001073326.1, XP_006528875.1, NP_001277375.1, XP_036017827.1, XP_036017826.1, XP_036017832.1, XP_036017831.1, XP_006528887.1, XP_030107193.1, XP_006528871.1, XP_006528873.1, XP_036017828.1, XP_036017833.1, XP_036017834.1, XP_006528877.1, XP_030107194.1, NP_001073317.1, XP_006528882.1, XP_006528869.1, XP_036017829.1, XP_006528874.1, XP_017173968.1, XP_006528892.1
Others
UniRef100: UniRef100_Q8CJ12, UniRef100_Q14BH6
UniRef90: UniRef90_Q8CJ12
UniRef50: UniRef50_Q8IZP9
UniGene: Mm.213016
CCDS: CCDS41199.1, CCDS41196.1, CCDS41197.1, CCDS72459.1, CCDS81192.1

全选

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研究热度

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