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23678 SGK3

23678

SGK3

serum/glucocorticoid regulated kinase family member 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition serum/glucocorticoid regulated kinase family member 3

研究结论

Date Results Publications
2021-02-06 13:50:00 Mutation of SGK3, a Novel Regulator of Renal Phosphate Transport, Causes Autosomal Dominant Hypophosphatemic Rickets. 31821448
2020-04-11 10:30:00 In patients with polycystic ovary syndrome, miR-335-5p is involved in granulosa cells proliferation by reducing SGK3 expression. 30328340
2019-08-17 10:50:00 Study data from human hepatocellular carcinoma (HCC) liver samples, human HCC cells, and Sgk3 knockout mice model suggest that SGK3 plays a role in transducing helical domain mutant PIK3CA signaling during liver tumor development. 30975125
2019-05-11 13:08:00 overexpression of INPP4B promotes NPM1-mutated leukemia cell proliferation through SGK3 activation. High levels of INPP4B are at least partially induced by the NPM1 mutant via ERK/Ets-1 signaling. 29343273
2018-09-08 11:14:00 Mechanism of activation of SGK3 by IGF1 via the class 1 and class 3 phosphatidylinositol 3-kinases has been described. 29150437

名称对应

Type IDs
Synonymous CISK, SGK2, SGKL
Gene
UniProtKB-ID: SGK3_HUMAN, Q5H9Q5_HUMAN, Q53EW6_HUMAN, A0A024R807_HUMAN
UniprotKB: Q96BR1, Q5H9Q5, Q53EW6, A0A024R807
UniParc: UPI00004C42AA, UPI000050A9FE, UPI000015D94C, UPI000013591F
EMBL: AF085233, AC011031, CH471068, CR933673, AC090154, AF169035, AK223523, BC015326, AK074666, AK291428
Ensembl: ENSG00000104205
KO: hsa:23678, hsa:100533105
Nucleutide sequences
EMBL-CDS: AAH15326.1, AAF12758.1, EAW86919.1, AAF27051.2, BAG51984.1, BAF84117.1, CAI45969.1, BAD97243.1, EAW86920.1
Gene_ORFName: hCG_18389
Ensembl_TRS: ENST00000521198, ENST00000396596, ENST00000520976, ENST00000522398, ENST00000345714
Protein sequencees
Ensembl_PRO: ENSP00000430256, ENSP00000331816, ENSP00000430463, ENSP00000430691, ENSP00000379842
RefSeq: NP_733827.2, NP_001028750.1, NP_037389.4
Others
UniRef100: UniRef100_Q96BR1, UniRef100_Q5H9Q5, UniRef100_Q53EW6
UniRef90: UniRef90_Q96BR1
UniRef50: UniRef50_Q96BR1
UniGene: Hs.613417, Hs.733251
CCDS: CCDS6196.1, CCDS6195.1

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