| Type | Description |
|---|---|
| Definition | SH3 domain binding protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 10:07:00 | The data uncover the tumor-suppressive role of SH3BP4 that functions as a negative feedback regulator of Wnt signaling through modulating beta-catenin's subcellular localization. | 30811977 |
| 2020-02-15 13:11:00 | A SNP in the 3'UTR of SH3BP4 (rs56161233) that overlaps predicted miR-100-binding sites and is predicted to disrupt several miRNA-mRNA interactions was associated with overall survival of laryngeal cancer. | 29880533 |
| 2018-06-02 11:19:00 | SH3BP4 has been identified as a novel pigmentation gene. The SH3BP4 is a direct target of miR-125b. The SH3BP4 is transcriptionally regulated by MITF as its direct target. | 28819321 |
| 2012-10-27 11:21:00 | SH3BP4 is a negative regulator of the Rag GTPase complex and amino acid-dependent mTORC1 signaling. | 22575674 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | BOG25, TTP |
| Gene |
UniProtKB-ID:
SH3B4_HUMAN
UniprotKB:
Q9P0V3
UniParc:
UPI000006DA47,
UPI0000EF88BA
EMBL:
AC114814,
DQ232895,
AC010148,
AF015043,
AF147747,
BC057396
Ensembl:
ENSG00000130147
KO:
hsa:23677
|
| Nucleutide sequences |
EMBL-CDS:
AAY24025.1,
AAD01551.1,
AAY14916.1,
AAH57396.1,
ABB18377.1,
AAF33022.1
Ensembl_TRS:
ENST00000344528,
ENST00000409212,
ENST00000392011
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000340237,
ENSP00000386862,
ENSP00000375867
RefSeq:
NP_001358231.1,
NP_001358232.1,
NP_001358233.1,
NP_055336.1,
NP_001358234.1,
NP_001358235.1,
XP_011509195.1
|
| Others |
UniRef100:
UniRef100_Q9P0V3
UniRef90:
UniRef90_Q9P0V3
UniRef50:
UniRef50_Q9P0V3
UniGene:
Hs.516777
CCDS:
CCDS2513.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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