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236539 Phgdh

236539

Phgdh

3-phosphoglycerate dehydrogenase

protein-coding

Mus musculus

基因描述

Type Description
Definition 3-phosphoglycerate dehydrogenase

研究结论

Date Results Publications
2021-03-20 13:23:00 Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation. 32023468
2020-05-02 11:15:00 Reduced Phgdh expression and serine levels are closely associated with the development of Fatty Liver Disease. 31678070
2019-03-30 13:02:00 PHGDH-mediated serine biosynthesis has important roles in adipose tissue glucose metabolism and could be a therapeutic target for diabetes in humans 30180949
2014-04-05 10:56:00 These results indicate that the PHGDH gene expression, dictated by IL-2R signaling, is a crucial event for DNA synthesis during S phase of activated T cells. 24434753
2013-10-19 12:18:00 Using transgenic mice expressing enhanced GFP under the Srr promoter and mice with targeted deletion of Srr or 3-Phosphoglycerate dehydrogenase, we demonstrate predominantly neuronal sources of d-serine dependent on astrocytic supply of l-serine. 23884950

名称对应

Type IDs
Synonymous 3-PGDH, 3PGDH, 4930479N23, A10, PGAD, PGD, PGDH, SERA
Gene
UniProtKB-ID: SERA_MOUSE
UniprotKB: Q61753
UniParc: UPI0000237ED2
EMBL: BC110673, AK076815, L21027, BC086668, AK169684, AB128936
Ensembl: ENSMUSG00000053398
KO: mmu:236539
Nucleutide sequences
EMBL-CDS: BAC36494.1, BAD08449.1, AAB67986.1, AAI10674.1, BAE41303.1, AAH86668.1
Ensembl_TRS: ENSMUST00000065793
Protein sequencees
Ensembl_PRO: ENSMUSP00000064755
RefSeq: NP_058662.2
Others
UniRef100: UniRef100_Q61753
UniRef90: UniRef90_Q61753
UniRef50: UniRef50_O43175
UniGene: Mm.16898, Mm.371997
CCDS: CCDS17663.1

全选

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