| Type | Description |
|---|---|
| Definition | ADP ribosylation factor interacting protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-07-02 10:26:00 | The data indicate that arfaptin 2 is the first molecule to regulate NF-kappaB signaling by interacting with the functional IkappaB kinase complex but not by direct inhibiting IKKbeta phosphorylation. | 26296658 |
| 2013-11-30 12:36:00 | both Arf1 activation and high membrane curvature are required for efficient recruitment of Arfaptin2 to membranes | 23638170 |
| 2013-08-31 12:04:00 | The binding of arfaptin1, but not arfaptin2, to PI(4)P is regulated by protein kinase D (PKD) mediated phosphorylation at Ser100 within the AH. | 23695357 |
| 2012-10-20 10:51:00 | The Arl1.Arfaptin-2 BAR structure suggests that one of the two Arl1 molecules competes with Rac1, which binds to the concave face of the Arfaptin-2 BAR homodimer and may hinder its membrane association. | 22679020 |
| 2010-01-21 00:00:00 | arfaptin 2 phosphorylation at Ser260 by Akt inhibits PolyQ-huntingtin-induced toxicity by rescuing proteasome impairment | 15809304 |
| Type | IDs |
|---|---|
| Synonymous | POR1 |
| Gene |
UniProtKB-ID:
ARFP2_HUMAN,
A0A087X1E4_HUMAN,
B4DUZ3_HUMAN,
B4DXH2_HUMAN
UniprotKB:
P53365,
A0A087X1E4,
B4DUZ3,
B4DXH2
UniParc:
UPI000016AEE9,
UPI000012566A,
UPI0002176A53,
UPI00017A87C7,
UPI00017A7D50,
UPI00017A8133
EMBL:
CH471064,
X97567,
AK300855,
AK301856,
AC084337,
AK304512,
BC000392,
AK301972,
U52522
Ensembl:
ENSG00000132254
KO:
hsa:23647
|
| Nucleutide sequences |
EMBL-CDS:
AAH00392.1,
BAG63298.1,
AAA97924.1,
EAW68708.1,
BAG65318.1,
CAA66179.1,
EAW68707.1,
BAG62505.1,
BAG63384.1
Ensembl_TRS:
ENST00000396777,
ENST00000445086,
ENST00000254584,
ENST00000423813,
ENST00000614314
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000398375,
ENSP00000379998,
ENSP00000254584,
ENSP00000391427,
ENSP00000484121
RefSeq:
NP_001357342.1,
NP_001357340.1,
NP_001363490.1,
NP_001363492.1,
NP_001229785.1,
NP_001363488.1,
NP_001363493.1,
NP_036534.1,
NP_001357338.1,
NP_001229784.1,
NP_001363491.1,
NP_001357335.1,
NP_001357341.1,
NP_001357337.1,
NP_001363487.1,
NP_001229783.1,
NP_001363489.1
|
| Others |
UniRef100:
UniRef100_A0A087X1E4,
UniRef100_B4DUZ3,
UniRef100_P53365,
UniRef100_B4DXH2
UniRef90:
UniRef90_P53365,
UniRef90_A0A087X1E4
UniRef50:
UniRef50_P53365,
UniRef50_A0A1B8XSX6
UniGene:
Hs.75139,
Hs.732203
CCDS:
CCDS55740.1,
CCDS55739.1,
CCDS7765.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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