| Type | Description |
|---|---|
| Definition | leucine rich repeat containing 6 |
| Date | Results | Publications |
|---|---|---|
| 2018-08-25 12:07:00 | Our study not only further supported the importance of LRRC6 in Primary ciliary dyskinesia (PCD), but also expanded the spectrum of LRRC6 mutations and will contribute to the genetic diagnosis and counseling of PCD patients. | 29511670 |
| 2013-12-21 10:35:00 | ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6. | 23891469 |
| 2013-09-21 10:43:00 | LRRC6 plays a role in dynein arm assembly or trafficking and when mutated leads to primary ciliary dyskinesia with laterality defects. | 23527195 |
| 2013-01-26 11:17:00 | Loss-of-function mutations in LRRC6, a gene essential for proper axonemal assembly of inner and outer dynein arms, cause primary ciliary dyskinesia. | 23122589 |
| Type | IDs |
|---|---|
| Synonymous | CILD19, LRTP, TSLRP |
| Gene |
UniProtKB-ID:
TILB_HUMAN
UniprotKB:
Q86X45
UniParc:
UPI000000DBC5,
UPI0000F3BE3B
EMBL:
BC047286,
U60666,
BC027589
Ensembl:
ENSG00000129295
KO:
hsa:23639
|
| Nucleutide sequences |
EMBL-CDS:
AAH27589.1,
AAH47286.1,
AAB02976.1
Ensembl_TRS:
ENST00000519595,
ENST00000620350
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000429791,
ENSP00000484634
RefSeq:
XP_016868787.1,
XP_011515252.1,
XP_016868785.1,
XP_016868786.1,
NP_001308894.1,
NP_001308891.1,
XP_006716601.2,
NP_001308890.1,
NP_036604.2,
NP_001308893.1,
NP_001308892.1,
NP_001308895.1
|
| Others |
UniRef100:
UniRef100_Q86X45
UniRef90:
UniRef90_Q86X45
UniRef50:
UniRef50_Q86X45
UniGene:
Hs.591865
CCDS:
CCDS6365.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员