| Type | Description |
|---|---|
| Definition | nucleoporin 62 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:14:00 | Complex 62 Promotes Metastasis of Gastric Cancer by Regulating Wnt/beta-Catenin and TGF-beta Signaling Pathways. | 33822519 |
| 2020-02-29 10:37:00 | Using a rapid and efficient protocol to differentiate mouse embryonic stem cells (ESC) to SpMNs and CrMNs, we now report that ESC-derived CrMNs accumulate less human (h)SOD1 and insoluble p62 than SpMNs over time | 31157617 |
| 2019-03-02 10:53:00 | XIAP enhanced cancer cell proliferation, viability, and colony formation in vitro via suppression of p62. In addition, we demonstrated that XIAP-enhanced tumor growth is dependent on depletion of p62 in vivo. Herein, we have therefore delineated a novel mechanism by which XIAP contributes to development and progression of breast and colon carcinoma | 30275562 |
| 2019-01-05 11:28:00 | ROCK-dependent phosphorylation of NUP62 regulates p63 nuclear transport and squamous cell carcinoma proliferation. | 29217659 |
| 2017-03-04 12:02:00 | it was revealed that a fraction of Nup62 was associated with mitotic spindle microtubule instead of spindle matrix, and the localization of Nup62 in the mitotic spindle depended on its three coiled-coil domains rather than Crm1, although Nup62 strongly interacted with Crm1 during mitosis. Moreover, depletion of Nup62 by small interference of RNA seriously induced the defects of chromosome alignment and spindle assembly | 27298184 |
| Type | IDs |
|---|---|
| Synonymous | IBSN, SNDI, p62 |
| Gene |
UniProtKB-ID:
NUP62_HUMAN,
A0A024QZF1_HUMAN
UniprotKB:
P37198,
A0A024QZF1
UniParc:
UPI000013EAFD
EMBL:
BC095410,
BC101105,
BC101107,
X58521,
AC011452,
AL162061,
BC101104,
BC050717,
CH471177,
BC101106,
BC014842,
CR541721,
AK125857,
BC003663
Ensembl:
ENSG00000213024
KO:
hsa:23636
|
| Nucleutide sequences |
EMBL-CDS:
AAI01107.1,
CAG46522.1,
AAH03663.1,
BAG54257.1,
AAH50717.1,
CAA41411.1,
CAB82399.1,
AAH14842.1,
AAI01105.1,
EAW52576.1,
AAI01108.1,
AAI01106.1,
AAH95410.1,
EAW52577.1,
EAW52578.1,
EAW52579.1
Gene_ORFName:
hCG_19665
Ensembl_TRS:
ENST00000597029,
ENST00000596217,
ENST00000352066,
ENST00000422090
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000407331,
ENSP00000471191,
ENSP00000305503,
ENSP00000473192
RefSeq:
NP_036478.2,
NP_714941.1,
NP_057637.2,
NP_714940.1,
NP_001180286.1
|
| Others |
UniRef100:
UniRef100_P37198
UniRef90:
UniRef90_P37198
UniRef50:
UniRef50_P37198
UniGene:
Hs.574492
CCDS:
CCDS12788.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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