| Type | Description |
|---|---|
| Definition | SPO11 initiator of meiotic double stranded breaks |
| Date | Results | Publications |
|---|---|---|
| 2017-03-11 11:33:00 | SPO11 gene C631T polymorphism may contribute as a genetic factor susceptible to cause male infertility in Chinese. | 28050928 |
| 2016-05-28 10:04:00 | Data suggest that the combined genotypes of glutathionine S-transferase GSTM1 (-/-), GSTT1 (+/+), GSTP1 (AA) and meiotic recombination protein SPO11 (CT) may be associated with idiopathic male infertility in ethnic Han Chinese. | 26663067 |
| 2015-05-30 12:36:00 | Polymorphisms within the SPO11 gene are linked to the susceptibility of azoospermia and oligozoospermia male infertility. | 25005169 |
| 2012-04-21 12:03:00 | SPO11 might has an effect on premorbid functioning, which increase susceptibility for idiopathic male reproduction | 21556891 |
| 2010-06-30 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 20378615 |
| Type | IDs |
|---|---|
| Synonymous | CT35, SPATA43, TOPVIA |
| Gene |
UniProtKB-ID:
SPO11_HUMAN
UniprotKB:
Q9Y5K1
UniParc:
UPI000007217D,
UPI0000135E5E
EMBL:
AF149310,
BC033591,
AF169385,
AL135939,
AY957583
Ensembl:
ENSG00000054796
KO:
hsa:23626
|
| Nucleutide sequences |
EMBL-CDS:
AAD52562.1,
AAD44812.1,
AAX44047.1,
AAH33591.1
Ensembl_TRS:
ENST00000371263,
ENST00000345868
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000360310,
ENSP00000316034
RefSeq:
XP_011527059.1,
XP_005260437.1,
XP_011527058.1,
NP_036576.1,
NP_937998.1,
XP_005260438.1,
XP_005260436.1,
XP_005260439.1
|
| Others |
UniRef100:
UniRef100_Q9Y5K1
UniRef90:
UniRef90_Q9Y5K1
UniRef50:
UniRef50_Q9Y5K1
UniGene:
Hs.159737
CCDS:
CCDS13456.1,
CCDS13457.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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