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23623 RUSC1

23623

RUSC1

RUN and SH3 domain containing 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition RUN and SH3 domain containing 1

研究结论

Date Results Publications
2019-06-01 12:43:00 The present study demonstrated that lncRNA RUSC1ASN promoted cell viability and metastasis via Wnt/betacatenin signaling in human breast cancer. 30569097
2019-01-05 12:06:00 AP-4 deficiency causes missorting of ATG9A in diverse cell types, including patient-derived cells, as well as dysregulation of autophagy. 30262884
2012-12-08 10:02:00 RUN domain of NESCA can bind H-Ras, a downstream signaling molecule of TrkA, with high affinity. Moreover, NESCA RUN can directly interact with TrkA. 22821014
2012-08-18 10:18:00 Nesca functions as an adapter involved in neuronal vesicular transport 22404429
2010-01-21 00:00:00 Data show that NESCA and NEMO interact by their N-terminal region, that NESCA directly associates with TRAF6, which in turn catalyzes NESCA polyubiquitination, and that NESCA overexpression strongly inhibits TRAF6-mediated polyubiquitination of NEMO. 19365808

名称对应

Type IDs
Synonymous NESCA
Gene
UniProtKB-ID: RUSC1_HUMAN, B4DQB8_HUMAN
UniprotKB: Q9BVN2, B4DQB8
UniParc: UPI000046FDA5, UPI000046FDA7, UPI000046FDA6, UPI00017A79EC, UPI0000073243
EMBL: AL139410, BC025680, CH471121, BX640612, AK074982, AK125378, AK314559, AK055451, AB026894, AK298730, AL080083, BC001045, BC052277
Ensembl: ENSG00000160753
KO: hsa:23623
Nucleutide sequences
EMBL-CDS: BAG52045.1, CAE45718.1, EAW53072.1, CAB45702.1, AAH01045.1, AAH52277.1, BAG54191.1, EAW53069.1, BAG37144.1, EAW53071.1, BAA77507.2, BAG60880.1
Ensembl_TRS: ENST00000368347, ENST00000368354, ENST00000368349, ENST00000368352, ENST00000292254
Protein sequencees
Ensembl_PRO: ENSP00000357333, ENSP00000357331, ENSP00000357336, ENSP00000292254, ENSP00000357338
RefSeq: NP_001098675.1, NP_001098674.1, NP_001265156.1, NP_001098673.1, XP_006711320.1, XP_016856381.1, XP_006711317.1, NP_001265158.1, XP_016856380.1, NP_001265159.1, NP_001265157.1, NP_055143.2, XP_006711319.1
Others
UniRef100: UniRef100_Q9BVN2, UniRef100_B4DQB8
UniRef90: UniRef90_Q9BVN2, UniRef90_B4DQB8
UniRef50: UniRef50_Q9BVN2, UniRef50_G3X0T9
UniGene: Hs.226499
CCDS: CCDS41411.1, CCDS41410.1, CCDS41412.1, CCDS1112.1

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