| Type | Description |
|---|---|
| Definition | beta-secretase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:09:00 | Flavonoids as BACE1 inhibitors: QSAR modelling, screening and in vitro evaluation. | 33010267 |
| 2021-02-27 13:50:00 | The EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer's Disease Models. | 32408680 |
| 2021-01-16 15:57:00 | miR-16-5p and miR-19b-3p prevent amyloid beta-induced injury by targeting BACE1 in SH-SY5Y cells. | 31876684 |
| 2020-12-12 13:29:00 | Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease. | 32917964 |
| 2020-12-05 13:04:00 | Proximity ligation assay reveals both pre- and postsynaptic localization of the APP-processing enzymes ADAM10 and BACE1 in rat and human adult brain. | 32019490 |
| Type | IDs |
|---|---|
| Synonymous | ASP2, BACE, HSPC104 |
| Gene |
UniProtKB-ID:
BACE1_HUMAN,
A0A024R3D7_HUMAN,
B7Z3K2_HUMAN,
B7Z3Z4_HUMAN,
A0A024R3E8_HUMAN,
A0A024R3D5_HUMAN,
A0A024R3F9_HUMAN,
Q5W9H2_HUMAN
UniprotKB:
P56817,
A0A024R3D7,
B7Z3K2,
B7Z3Z4,
A0A024R3E8,
A0A024R3D5,
A0A024R3F9,
Q5W9H2
UniParc:
UPI000002A4AC,
UPI0001914CBB,
UPI000002A4AD,
UPI0000EE3A21,
UPI000045239E,
UPI0000048186,
UPI000002A4AE
EMBL:
AB050436,
AB177847,
AB050438,
CH471065,
AF200343,
AF204943,
AP000892,
AB032975,
AF338817,
AF338816,
AF200193,
BC065492,
AF190725,
AB050437,
EF444940,
AK296535,
AF201468,
DQ007053,
AK296015
Ensembl:
ENSG00000186318
KO:
hsa:23621
|
| Nucleutide sequences |
EMBL-CDS:
AAH65492.1,
AAF13715.1,
BAB40933.1,
AAY16982.1,
AAK38375.1,
BAA86463.2,
EAW67313.1,
AAF17079.1,
AAF18982.1,
ACA05927.1,
AAK38374.1,
AAF04142.1,
AAF26367.1,
BAB40932.1,
BAB40931.1,
EAW67317.1,
BAH12238.1,
BAH12380.1,
EAW67315.1,
EAW67316.1,
EAW67311.1,
EAW67309.1,
EAW67312.1,
EAW67308.1,
EAW67310.1,
BAD66825.1
Gene_ORFName:
hCG_37942,
hCG_37942,
hCG_37942,
hCG_37942,
hCG_37942
Ensembl_TRS:
ENST00000513780,
ENST00000392937,
ENST00000445823,
ENST00000313005,
ENST00000428381,
ENST00000510630
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000402228,
ENSP00000403685,
ENSP00000424536,
ENSP00000475405,
ENSP00000422461,
ENSP00000318585
RefSeq:
NP_620427.1,
NP_001193978.1,
NP_620428.1,
NP_620429.1,
NP_001193977.1,
NP_036236.1
|
| Others |
UniRef100:
UniRef100_A0A024R3E8,
UniRef100_A0A024R3F9,
UniRef100_B7Z3Z4,
UniRef100_P56817,
UniRef100_A0A024R3D5,
UniRef100_B7Z3K2
UniRef90:
UniRef90_A0A024R3E8,
UniRef90_A0A024R3D5,
UniRef90_P56817,
UniRef90_B7Z3K2,
UniRef90_A0A2K5YMQ2,
UniRef90_A0A2Y9K4N9
UniRef50:
UniRef50_A0A3Q1M509,
UniRef50_A0A480XVZ0,
UniRef50_P56817,
UniRef50_A0A4X1SVF2,
UniRef50_Q1KLR6
UniGene:
Hs.504003
CCDS:
CCDS8383.1,
CCDS44741.1,
CCDS44739.1,
CCDS44740.1,
CCDS55786.1,
CCDS55787.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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