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23616 SH3BP1

23616

SH3BP1

SH3 domain binding protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition SH3 domain binding protein 1

研究结论

Date Results Publications
2018-11-03 10:03:00 Study demonstrated a high SH3BP1 expression in cervical cancer tissues and correlated with a shorter overall survival. Its expression is even higher in cisplatin resistant cervical neoplasm tissues compared to that of the cisplatin-sensitive ones. Furthermore, SH3BP1 plays an important role in the regulation of cervical cancer cell invasion, migration, and chemoresistance through Rac1/Wav2. 28786507
2017-02-18 10:35:00 SH3BP1 promoted VEGF secretion via Rac1-WAVE2 signaling, so as to exert an augmentation on cell invasion and microvessel formation. 26933917
2014-09-27 12:05:00 The identification and characterization of SH3BP1 as a novel downstream effector of Sema3E-PlexinD1 provides an explanation for how extracellular signals are translated into cytoskeletal changes and unique cell behavior. 24841563
2013-07-27 10:52:00 Splicing of SH3BP1 and CIN gene loci produces the novel brain specific splice variant BGIN. 23223568
2012-11-17 10:24:00 Epithelial junction formation and morphogenesis require a dual activity complex, containing SH3BP1 and CapZ, that is recruited to sites of active membrane remodeling to guide Cdc42 signaling and cytoskeletal dynamics. 22891260

名称对应

Type IDs
Synonymous ARHGAP43
Gene
UniProtKB-ID: 3BP1_HUMAN, A0A2X0SFX7_HUMAN
UniprotKB: Q9Y3L3, A0A2X0SFX7
UniParc: UPI0000403134, UPI000004EE00
EMBL: AK124370, CH471095, Z83844, CR456576, AL157480, BC008282, LS482417
Ensembl: ENSG00000100092
KO: hsa:23616
Nucleutide sequences
EMBL-CDS: CAG30462.1, CAB75671.2, AAH08282.1, BAC85842.1, EAW60174.1, SPT35794.1
Gene_ORFName: hCG_41861
Ensembl_TRS: ENST00000417536, ENST00000649765
Protein sequencees
Ensembl_PRO: ENSP00000497104, ENSP00000411979
RefSeq: NP_001336984.1, NP_061830.3
Others
UniRef100: UniRef100_Q9Y3L3
UniRef90: UniRef90_Q9Y3L3
UniRef50: UniRef50_Q9Y3L3
UniGene: Hs.601143
CCDS: CCDS13952.2

全选

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研究热度

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