| Type | Description |
|---|---|
| Definition | makorin ring finger protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:25:00 | Ubiquitination of IGF2BP3 by E3 ligase MKRN2 regulates the proliferation and migration of human neuroblastoma SHSY5Y cells. | 32560817 |
| 2019-03-30 12:54:00 | Results suggested that MKRN2 inhibited NSCLC progression by reducing the metastatic potential of cancer cells. Our findings provide critical insight into the association of MKRN2 expression with favorable clinicopathological characteristics in NSCLC patients. | 30103781 |
| 2018-12-01 11:17:00 | These results delineate a novel role of MKRN2 in negatively regulating NF-kappaB-mediated inflammatory responses, cooperatively with PDLIM2. | 28378844 |
| 2015-12-26 10:58:00 | Over-expression of MKRN2 in K562 cells increased cell proliferation. Our results indicated possible roles of MKRN2 in normal and malignant hematopoiesis. | 24675897 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | 21048031 |
| Type | IDs |
|---|---|
| Synonymous | HSPC070, RNF62 |
| Gene |
UniProtKB-ID:
MKRN2_HUMAN
UniprotKB:
Q9H000
UniParc:
UPI000007116E,
UPI000047FF00
EMBL:
AF161555,
AF277164,
BC015715,
AL834512,
AF277169,
BC001799,
AF277170,
AF277168,
CH471055,
AF277165,
AK298463,
AK091318,
AF277166,
AF277167,
AF302084,
AC018500
Ensembl:
ENSG00000075975
KO:
hsa:23609
|
| Nucleutide sequences |
EMBL-CDS:
BAG52337.1,
AAH15715.1,
CAD39168.1,
EAW64133.1,
AAG27595.1,
BAG60676.1,
AAF29042.2,
EAW64132.1,
AAG30426.1,
AAH01799.2
Gene_ORFName:
HSPC070
Ensembl_TRS:
ENST00000170447,
ENST00000411987
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000170447,
ENSP00000396340
RefSeq:
NP_001258636.1,
NP_054879.3
|
| Others |
UniRef100:
UniRef100_Q9H000
UniRef90:
UniRef90_Q9H000
UniRef50:
UniRef50_Q9H000
UniGene:
Hs.591666
CCDS:
CCDS63545.1,
CCDS33702.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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