| Type | Description |
|---|---|
| Definition | origin recognition complex subunit 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:23:00 | Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA. | 32986843 |
| 2017-07-01 12:19:00 | The 11-year-old boy with Meier-Gorlin syndrome (MGS) has a homozygous mutation in origin recognition complex, subunit 6 (ORC6) gene mapped to chromosome 16, and his father with heterozygote carrier of ORC6 gene. | 28186598 |
| 2016-04-30 11:19:00 | The present report expands the clinical phenotype associated with ORC6 mutations to include severely abnormal embryological development suggesting a possible genotype-phenotype correlation. | 25691413 |
| 2015-04-04 12:20:00 | our results suggest that Meier-Gorlin syndrome mutations in Orc6 impair the formation of ORC hexamers, interfering with appropriate ORC functions | 24137536 |
| 2012-01-07 10:48:00 | findings show that Orc6 not only interacts with Orc1-Orc5 but also with the initiation factor Cdc6, and that Orc6 functions at different stages of the replication initiation process. | 21461783 |
| Type | IDs |
|---|---|
| Synonymous | ORC6L |
| Gene |
UniProtKB-ID:
ORC6_HUMAN,
A0A024R6R3_HUMAN
UniprotKB:
Q9Y5N6,
A0A024R6R3
UniParc:
UPI0000130E64
EMBL:
CH471092,
BC063565,
AK024019,
BC039032,
AF139658
Ensembl:
ENSG00000091651
KO:
hsa:23594
|
| Nucleutide sequences |
EMBL-CDS:
AAH63565.1,
EAW82685.1,
BAG51251.1,
AAH39032.1,
AAD32666.1,
EAW82686.1
Gene_ORFName:
hCG_32369
Ensembl_TRS:
ENST00000219097
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000219097
RefSeq:
NP_055136.1,
XP_011521280.1
|
| Others |
UniRef100:
UniRef100_Q9Y5N6
UniRef90:
UniRef90_Q9Y5N6
UniRef50:
UniRef50_Q9Y5N6
UniGene:
Hs.49760
CCDS:
CCDS10722.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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