| Type | Description |
|---|---|
| Definition | LEM domain containing 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:54:00 | Melorheostosis and Osteopoikilosis Clinical and Molecular Description of an Italian Case Series. | 31129707 |
| 2019-11-30 10:58:00 | Here we describe the unusual case of a 60-year-old woman with isolated nevus elasticus and a mutation in the LEMD3 (LEM Domain Containing 3) gene. | 29465813 |
| 2019-07-20 12:14:00 | analysis of the structural basis for R-SMAD recognition by MAN1 using SMAD2-MAN1 and SMAD1-MAN1 complex structures | 30321401 |
| 2019-04-27 10:33:00 | LEMD3 is cleaved by PPM1a into fragments that enter the cytosol to bind SMAD2 and SMAD3, thereby antagonizing signaling initiated by stiffness-triggered activity of TGFbeta. | 30108174 |
| 2018-01-06 10:24:00 | studies demonstrated that lower levels of MAN1 in differentiating MSC are associated with higher osteogenesis and lower adipogenesis. High levels of MAN1 only affected adipogenesis. | 28449239 |
| Type | IDs |
|---|---|
| Synonymous | MAN1 |
| Gene |
UniProtKB-ID:
MAN1_HUMAN,
A0A024RBB9_HUMAN
UniprotKB:
Q9Y2U8,
A0A024RBB9
UniParc:
UPI000012EB75
EMBL:
AF180142,
AF112299,
CH471054,
AF180136,
AF180139,
AF180137,
AF180135,
AF180140,
AF180138,
AF263918,
AL137533,
AF180141
Ensembl:
ENSG00000174106
KO:
hsa:23592
|
| Nucleutide sequences |
EMBL-CDS:
AAD31593.2,
AAF73293.1,
CAB70796.1,
EAW97148.1,
EAW97149.1
Gene_ORFName:
hCG_22729
Ensembl_TRS:
ENST00000308330
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000308369
RefSeq:
NP_055134.2,
NP_001161086.1
|
| Others |
UniRef100:
UniRef100_Q9Y2U8
UniRef90:
UniRef90_Q9Y2U8
UniRef50:
UniRef50_Q9Y2U8
UniGene:
Hs.744150
CCDS:
CCDS8972.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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