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235712 Mrgpra2b

235712

Mrgpra2b

MAS-related GPR, member A2B

protein-coding

Mus musculus

基因描述

Type Description
Definition MAS-related GPR, member A2B

研究结论

Date Results Publications
2017-12-02 11:09:00 Ultra-high doses did not influence the ACE2/AT2R/Mas axis and promoted renal injury with increased renal ERK1/2 activation and exaggerated fibronectin expression in db/db mice. Our study demonstrates dose-related effects of candesartan in diabetic nephropathy: intermediate-high dose candesartan is renoprotective, whereas ultra-high dose candesartan induces renal damage. 27612496
2010-10-23 10:43:00 data suggest that members of the Mrgpr family, in particular MrgprC11, may constitute an endogenous inhibitory mechanism for regulating persistent pain in mice 20724664
2010-01-21 00:00:00 Mas deficiency in FVB/N mice leads to dramatic changes in glucose and lipid metabolisms, inducing a metabolic syndrome-like state. 18025412
2010-01-21 00:00:00 Deletion of the Mas protooncogene abolishes the binding of Ang-(1-7) to mouse kidneys. Mas is a functional receptor for Ang-(1-7) 12829792

名称对应

Type IDs
Synonymous MrgA2, Mrgpra2
Gene
UniProtKB-ID: MRGA2_MOUSE, E9QNZ7_MOUSE
UniprotKB: Q91WW4, E9QNZ7
UniParc: UPI0000047B9F, UPI0000029430
EMBL: AC138678, AY042192, BC064040
Ensembl: ENSMUSG00000096719
KO: mmu:235712, mmu:668727
Nucleutide sequences
EMBL-CDS: AAK91788.1, AAH64040.1
Ensembl_TRS: ENSMUST00000119798
Protein sequencees
Ensembl_PRO: ENSMUSP00000113310
RefSeq: NP_001368930.1, NP_694741.2
Others
UniRef100: UniRef100_E9QNZ7, UniRef100_Q91WW4
UniRef90: UniRef90_Q91WW4
UniRef50: UniRef50_Q91WW3
UniGene: Mm.425459

全选

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研究热度

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