| Type | Description |
|---|---|
| Definition | lysophosphatidic acid receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:57:00 | Lysophosphatidic acid receptor LPA3 prevents oxidative stress and cellular senescence in Hutchinson-Gilford progeria syndrome. | 31714004 |
| 2020-06-20 10:41:00 | miR-15b represses the proliferation and drives the senescence and apoptosis of ovarian cancer cells through the suppression of LPAR3 and the PI3K/Akt pathway, highlighting an antitumorigenic role of miR-15b. | 31140597 |
| 2020-01-25 10:21:00 | Study also identifies that LPAR3 increases miR-122-5p expression, which occurs mechanistically through the SH3 domain and helps explain why miR-122-5p increases are detected in cancer patient serum. LPAR3 is partially responsible for the production and secretion of miR-122-5p, found in the serum of a wide variety of patients with cancer. | 30266753 |
| 2019-08-24 12:08:00 | LPAR3 was differently expressed in melanosis coli tissues.LPAR3 expression was related to cell apoptosis. | 30559147 |
| 2018-11-03 10:20:00 | Using pharmacological activators and shRNA knockdown experiments, we demonstrate that activation of LPA3 inhibits megakaryopoiesis in human HSCs. In addition, pharmacological activation of LPA3 suppressed thrombopoiesis in zebrafish. | 29239275 |
| Type | IDs |
|---|---|
| Synonymous | EDG7, Edg-7, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3 |
| Gene |
UniProtKB-ID:
LPAR3_HUMAN
UniprotKB:
Q9UBY5
UniParc:
UPI000003CAC0
EMBL:
BC126268,
AF127138,
AF186380,
BC126270,
AY322547
Ensembl:
ENSG00000171517
KO:
hsa:23566
|
| Nucleutide sequences |
EMBL-CDS:
AAP84360.1,
AAF00530.1,
AAI26269.1,
AAD56311.1,
AAI26271.1
Ensembl_TRS:
ENST00000440886,
ENST00000370611
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359643,
ENSP00000395389
RefSeq:
NP_036284.1,
XP_024301895.1,
XP_024301896.1
|
| Others |
UniRef100:
UniRef100_Q9UBY5
UniRef90:
UniRef90_Q9UBY5
UniRef50:
UniRef50_Q9UBY5
UniGene:
Hs.674915
CCDS:
CCDS700.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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