| Type | Description |
|---|---|
| Definition | protease, serine 50 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 10:41:00 | TSP50 expression at embryonic day 6.5 (E6.5), day 8.5 (E8.5) and day 10.5 (E10.5) was increasingly enhanced, However, the expression of TSP50 decreased gradually in the development and differentiation of cardiac myocyte from E12.5 to postnatal (P0). | 29842883 |
| 2011-10-15 11:29:00 | findings indicate that BORIS-induced expression of TSP50 is governed by accessibility and binding of BORIS to the promoter | 21659515 |
| 2011-07-23 10:31:00 | TSP50 promotes cell proliferation, at least partially, through activation of the NF-kappaB signalling pathway. | 21385156 |
| 2011-03-12 10:29:00 | results showed that downregulation of TSP50 expression in P19 embryonal carcinoma stem cells not only reduced cell proliferation, colony formation, and migration but also induced cell apoptosis | 21086474 |
| 2010-01-21 00:00:00 | TSP50 may perform a critical biologic function in mammalian spermatogenesis. It may be a new type of threonine protease whose linear catalytic structure is similar to many serine proteases, except for a Thr-for-Ser residual catalytic site substitution. | 15491742 |
| Type | IDs |
|---|---|
| Synonymous | 79H19C, Tsp50 |
| Gene |
UniProtKB-ID:
TSP50_MOUSE
UniprotKB:
Q8BLH5
UniParc:
UPI00000EB458
EMBL:
AF481144,
BC150686,
AC139378,
AK045168
Ensembl:
ENSMUSG00000048752
KO:
mmu:235631
|
| Nucleutide sequences |
EMBL-CDS:
BAC32245.1,
AAI50687.1,
AAM89223.1
Ensembl_TRS:
ENSMUST00000051097
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000059668
RefSeq:
NP_001366296.1,
NP_666339.2
|
| Others |
UniRef100:
UniRef100_Q8BLH5
UniRef90:
UniRef90_Q8BLH5
UniRef50:
UniRef50_Q8BLH5
UniGene:
Mm.102265
CCDS:
CCDS23577.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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