| Type | Description |
|---|---|
| Definition | SET domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | SETD2 deficiency accelerates MDS-associated leukemogenesis via S100a9 in NHD13 mice and predicts poor prognosis in MDS. | 32202636 |
| 2020-11-28 13:16:00 | NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing. | 32929285 |
| 2020-10-24 13:55:00 | Loss of Setd2 promotes Kras-induced acinar-to-ductal metaplasia and epithelia-mesenchymal transition during pancreatic carcinogenesis. | 31300513 |
| 2020-06-06 12:17:00 | SETD2 mutations have a role in chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints | 30967619 |
| 2020-01-04 10:48:00 | Setd2 is required for optimal V(D)J recombination and normal lymphocyte development. | 31350389 |
| Type | IDs |
|---|---|
| Synonymous | 4921524K10Rik, BC031601, KMT3A |
| Gene |
UniProtKB-ID:
SETD2_MOUSE
UniprotKB:
E9Q5F9
UniParc:
UPI00017EE9F3,
UPI00035BEEF3
EMBL:
AK173246,
BC031601,
BC059049,
AC132103
Ensembl:
ENSMUSG00000044791
KO:
mmu:235626
|
| Nucleutide sequences |
EMBL-CDS:
AAH59049.1,
BAD32524.1,
AAH31601.1
Ensembl_TRS:
ENSMUST00000153838
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000116313
RefSeq:
XP_006512154.1,
XP_006512155.1,
XP_006512151.1,
XP_036010809.1,
XP_036010810.1,
XP_036010811.1,
NP_001074809.2,
XP_036010808.1
|
| Others |
UniRef100:
UniRef100_E9Q5F9
UniRef90:
UniRef90_E9Q5F9
UniRef50:
UniRef50_E9Q5F9
UniGene:
Mm.288949
CCDS:
CCDS40781.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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