| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 28 |
| Date | Results | Publications |
|---|---|---|
| 2016-01-30 10:13:00 | In mice, an unusually direct antagonism between an E3 ligase and a deubiquitinase, Fbw7 and Usp28, modulate intestinal homeostasis and cancer. | 25716680 |
| 2015-07-25 11:38:00 | Dual regulation of Fbw7 activity by Usp28 is a safeguard mechanism for maintaining physiological levels of proto-oncogenic Fbw7 substrates, which is equivalently disrupted by loss or overexpression of Usp28. | 25437563 |
| 2015-02-21 10:17:00 | identified Usp28 as a c-MYC target gene highly expressed in colorectal cancers, which indicates that USP28 and c-MYC form a positive feedback loop that maintains high c-MYC protein levels in tumors | 24960159 |
| Type | IDs |
|---|---|
| Synonymous | 9830148O20Rik, AU022237, mKIAA1515 |
| Gene |
UniProtKB-ID:
UBP28_MOUSE
UniprotKB:
Q5I043
UniParc:
UPI000023B74E,
UPI00001C43E0
EMBL:
BC066033,
AK129380,
AK052442,
BC088733
Ensembl:
ENSMUSG00000032267
KO:
mmu:235323
|
| Nucleutide sequences |
EMBL-CDS:
BAC98190.1,
AAH88733.1,
BAC34993.1,
AAH66033.1
Ensembl_TRS:
ENSMUST00000213874,
ENSMUST00000047349
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000149207,
ENSMUSP00000047467
RefSeq:
XP_030100184.1,
XP_036010786.1,
XP_006510327.1,
XP_006510323.1,
XP_006510324.1,
XP_006510326.1,
NP_001346668.1,
XP_006510322.1,
NP_780691.2
|
| Others |
UniRef100:
UniRef100_Q5I043
UniRef90:
UniRef90_Q5I043
UniRef50:
UniRef50_Q96RU2
UniGene:
Mm.21630
CCDS:
CCDS40613.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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