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23530 NNT

23530

NNT

nicotinamide nucleotide transhydrogenase

protein-coding

Homo sapiens

基因描述

Type Description
Definition nicotinamide nucleotide transhydrogenase

研究结论

Date Results Publications
2021-02-20 13:29:00 Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function. 32196080
2021-01-02 12:48:00 LncRNA NNT-AS1 regulates the progression of lung cancer through the NNT-AS1/miR-3666/E2F2 axis. 31957837
2020-02-29 11:29:00 Study looked at the expression of nicotinamide nucleotide transhydrogenase (NNT) and NNT-AS1 in the peripheral blood of multiple sclerosis patients to find their participation in the pathogenesis of this immune-related disorder. We detected up-regulation of NNT expression in male subjects aged over 50 compared with the corresponding control subjects. 31474168
2019-12-07 10:48:00 Low NNT expression is associated with gastric cancer. 31309731
2019-03-02 10:53:00 NNT knockdown in adrenocortical carcinoma increased intracellular levels of oxidative stress; this resulted in a pronounced suppression of cell proliferation and higher apoptotic rates, as well as sensitization of cells to chemically induced oxidative stress. 29850793

名称对应

Type IDs
Synonymous GCCD4
Gene
UniProtKB-ID: NNTM_HUMAN, A0A024R0C3_HUMAN, E9PCX7_HUMAN
UniprotKB: Q13423, A0A024R0C3, E9PCX7
UniParc: UPI000013D54F, UPI0001D3B294
EMBL: AC010435, U40490, Z50101, BC110543, AL831822, CH471119
Ensembl: ENSG00000112992
KO: hsa:23530
Nucleutide sequences
EMBL-CDS: AAI10544.1, CAD38536.1, AAC51914.1, CAA90428.1, EAW56074.1, EAW56073.1
Gene_ORFName: hCG_17428
Ensembl_TRS: ENST00000669601, ENST00000670904, ENST00000662525, ENST00000656666, ENST00000671668, ENST00000344920, ENST00000264663, ENST00000653251, ENST00000512996
Protein sequencees
Ensembl_PRO: ENSP00000499249, ENSP00000264663, ENSP00000499527, ENSP00000499639, ENSP00000343873, ENSP00000499611, ENSP00000499494, ENSP00000499281, ENSP00000426343
RefSeq: NP_892022.2, XP_006714524.1, XP_011512303.1, XP_024301777.1, XP_005248331.1, NP_001317955.1, XP_016864782.1, XP_005248332.1, NP_036475.3
Others
UniRef100: UniRef100_Q13423
UniRef90: UniRef90_Q13423
UniRef50: UniRef50_Q13423
UniGene: Hs.482043
CCDS: CCDS3949.1

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