| Type | Description |
|---|---|
| Definition | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 12:28:00 | analysis of structural basis for effector recognition in Rab35/ACAP2 and Rab35/RUSC2 complexes | 30905672 |
| 2020-02-15 13:01:00 | Elevated expression of circACAP2 in breast cancer tissues leads to malignant phenotype upon cancerous cells. CircACAP2-miR-29a/b-3p-COL5A1 axis leads to breast cancer tumorigenesis | 31863774 |
| 2018-10-20 10:32:00 | The down-regulation of circRNA-ACAP2 promoted miR-21-5p expression, which further suppressed the transcription and translation of Tiam1. | 30212824 |
| 2017-08-05 10:32:00 | Data suggest that Rab35, interacting with TBC1D10A, functions in vascular endothelial cells as a negative regulator of histamine-evoked, Ca2+-dependent Weibel-Palade body exocytosis, most likely acting through the downstream effectors ACAP2 and Arf6. (Rab35 = rab GTP-binding protein 53; TBC1D10A = TBC1 domain family member 10A; ACAP2 = centaurin beta2; Arf6 = ADP-ribosylation factor 6) | 28566286 |
| 2016-04-23 12:13:00 | ACAP2 is a functional homolog of C. elegans CNT-1 and its inactivation or downregulation in human cells may contribute to cancer development | 25853217 |
| Type | IDs |
|---|---|
| Synonymous | CENTB2, CNT-B2 |
| Gene |
UniProtKB-ID:
ACAP2_HUMAN
UniprotKB:
Q15057
UniParc:
UPI0000141A1A
EMBL:
BC060767,
AJ238248,
BC031005,
D26069,
AK290369,
CH471052
Ensembl:
ENSG00000114331
KO:
hsa:23527
|
| Nucleutide sequences |
EMBL-CDS:
CAB41450.1,
AAH60767.1,
AAH31005.1,
BAF83058.1,
EAW78027.1,
BAA05064.2
Ensembl_TRS:
ENST00000326793
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000324287
RefSeq:
XP_016861536.1,
XP_011510905.1,
XP_011510907.1,
XP_011510908.1,
NP_036419.3,
XP_011510906.1,
XP_016861537.1,
XP_016861535.1,
XP_006713620.1,
XP_011510904.1,
XP_016861538.1
|
| Others |
UniRef100:
UniRef100_Q15057
UniRef90:
UniRef90_Q15057
UniRef50:
UniRef50_Q15057
UniGene:
Hs.593373
CCDS:
CCDS33924.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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