| Type | Description |
|---|---|
| Definition | scaffold protein involved in DNA repair |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:31:00 | our study uncovers a protein complex, which consists of SWS1, SWSAP1, SPIDR and PDS5B, involved in DNA repair and provides insight into Shu complex function and composition. | 31665741 |
| 2017-07-22 12:35:00 | A biallelic mutation in SPIDR may be associated with ovarian dysgenesis in cases of autosomal recessive inheritance. | 27967308 |
| 2013-09-07 11:56:00 | KIAA0146 is also known as scaffolding protein involved in DNA repair (SPIDR), as a binding partner of FIGNL1 and established that KIAA0146/SPIDR acts with FIGNL1 in homologous recombination repair | 23754376 |
| 2013-09-07 11:45:00 | Consistent with its role as a scaffolding protein for the assembly of BLM and RAD51 foci, cells depleted of SPIDR show increased rate of sister chromatid exchange and defects in homologous recombination repair. | 23509288 |
| 2013-08-31 12:01:00 | The FRA8I fragile site includes KIAA0146, CEBPD and PRKDC and may have a role in colorectal cancer | 23603433 |
| Type | IDs |
|---|---|
| Synonymous | KIAA0146 |
| Gene |
UniProtKB-ID:
SPIDR_HUMAN
UniprotKB:
Q14159
UniParc:
UPI00017A6FEB,
UPI00017A84A9,
UPI0000253B92
EMBL:
AK303579,
AC233269,
AK294275,
AC142471,
AC024649,
AC023991,
AC104995,
D63480,
AC024451,
BC015561
Ensembl:
ENSG00000164808
KO:
hsa:23514
|
| Nucleutide sequences |
EMBL-CDS:
BAG64598.1,
BAA09767.1,
AAH15561.2,
BAG57563.1
Ensembl_TRS:
ENST00000518074,
ENST00000541342,
ENST00000297423
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000444061,
ENSP00000297423,
ENSP00000429487
RefSeq:
NP_001339875.1,
NP_001339877.1,
NP_001339861.1,
XP_016868768.1,
NP_001339869.1,
NP_001339878.1,
NP_001339886.1,
NP_001339879.1,
NP_001339881.1,
XP_016868759.1,
XP_024302885.1,
NP_001339885.1,
NP_001339874.1,
XP_016868762.1,
XP_016868758.1,
XP_016868763.1,
NP_001339871.1,
NP_001339876.1,
XP_016868765.1,
NP_001269848.1,
NP_001339860.1,
NP_001339872.1,
NP_001339867.1,
NP_001339873.1,
XP_016868770.1,
NP_001339884.1,
NP_001339888.1,
NP_001339889.1,
NP_001339882.1,
NP_001339880.1,
NP_001339868.1,
XP_016868757.1,
XP_016868760.1,
NP_001339866.1,
NP_001073863.1,
NP_001269845.1,
NP_001339870.1,
NP_001339862.1,
NP_001339863.1,
NP_001339864.1,
XP_024302884.1,
NP_001339890.1,
NP_001339865.1,
XP_016868769.1,
NP_001339887.1,
XP_011515799.1,
XP_016868778.1
|
| Others |
UniRef100:
UniRef100_Q14159
UniRef90:
UniRef90_Q14159
UniRef50:
UniRef50_Q14159
UniGene:
Hs.381058
CCDS:
CCDS43737.1,
CCDS64891.1,
CCDS64890.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员