| Type | Description |
|---|---|
| Definition | SUZ12 polycomb repressive complex 2 subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:18:00 | Human papillomavirus type 16 E7 oncoprotein-induced upregulation of lysine-specific demethylase 5A promotes cervical cancer progression by regulating the microRNA-424-5p/suppressor of zeste 12 pathway. | 32918895 |
| 2021-02-27 13:51:00 | Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells. | 33338397 |
| 2020-05-16 13:03:00 | we confirmed that miR-487b is a CRC suppressor that prevents the EMT process and targets MYC, SUZ12, and KRAS to inhibit the proliferation, migration and invasion of CRC cells. Meanwhile, miR-487b is negatively regulated by DNA methylation | 30791232 |
| 2020-05-09 13:14:00 | review the PRC2 complex and clinical syndromes of overgrowth and intellectual disability associated with core components EZH2, EED, and SUZ12 | 31724824 |
| 2020-05-09 10:34:00 | Pathogenic SUZ12 variants may be de novo or inherited, and are sometimes inherited from a mildly-affected parent | 31736240 |
| Type | IDs |
|---|---|
| Synonymous | CHET9, JJAZ1 |
| Gene |
UniProtKB-ID:
SUZ12_HUMAN,
J3QQW9_HUMAN
UniprotKB:
Q15022,
J3QQW9
UniParc:
UPI000006F727,
UPI0000D4979B
EMBL:
AC090616,
AC129917,
D63881,
BC015704
Ensembl:
ENSG00000178691
KO:
hsa:23512
|
| Nucleutide sequences |
EMBL-CDS:
AAH15704.1,
BAA09931.2
Ensembl_TRS:
ENST00000322652,
ENST00000580398
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316578,
ENSP00000463936
RefSeq:
NP_056170.2,
XP_016879898.1,
XP_006721857.1,
NP_001308136.1
|
| Others |
UniRef100:
UniRef100_J3QQW9,
UniRef100_Q15022
UniRef90:
UniRef90_Q15022,
UniRef90_J3QQW9
UniRef50:
UniRef50_Q6DC03,
UniRef50_Q15022
UniGene:
Hs.462732
CCDS:
CCDS11270.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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