| Type | Description |
|---|---|
| Definition | nucleoporin 188 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:08:00 | Differential turnover of Nup188 controls its levels at centrosomes and role in centriole duplication. | 32211895 |
| 2020-08-01 12:05:00 | results implicate bi-allelic loss-of-function NUP188 variants in a recessive syndrome characterized by a distinct neurologic, ophthalmologic, and facial phenotype | 32275884 |
| 2020-07-04 10:28:00 | Results identified Nup188 as a novel TDP-43 target which controls the mRNA splicing of Nup188. | 31527135 |
| 2017-06-24 11:39:00 | we show that knockdown of Nup188 or its binding partner Nup93 leads to a loss of cilia during embryonic development while leaving NPC function largely intact. Many data, including the localization of endogenous Nup188/93 at cilia bases, support their direct role at cilia. Super-resolution imaging of Nup188 shows two barrel-like structures | 27593162 |
| Type | IDs |
|---|---|
| Synonymous | KIAA0169, hNup188 |
| Gene |
UniProtKB-ID:
NU188_HUMAN
UniprotKB:
Q5SRE5
UniParc:
UPI00015B3BDE,
UPI000041A60F
EMBL:
BX537774,
AL592211,
BC040352,
D79991,
CH471090,
AL672142,
BC111045
Ensembl:
ENSG00000095319
KO:
hsa:23511
|
| Nucleutide sequences |
EMBL-CDS:
EAW87850.1,
AAI11046.1,
AAH40352.1,
CAD97835.1,
BAA11486.1
Ensembl_TRS:
ENST00000372577
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361658
RefSeq:
NP_056169.1
|
| Others |
UniRef100:
UniRef100_Q5SRE5
UniRef90:
UniRef90_Q5SRE5
UniRef50:
UniRef50_Q5SRE5
UniGene:
Hs.308340
CCDS:
CCDS35156.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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