| Type | Description |
|---|---|
| Definition | protein O-fucosyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:44:00 | poFUT1 promotes uterine angiogenesis and vascular remodeling via enhancing the O-fucosylation on uPA. | 31601791 |
| 2020-04-11 10:56:00 | PLAGL2 and POFUT1 were common and upregulated in tumor samples in colorectal cancer (CRC). Survival analysis of PLAGL2 and POFUT1 expression revealed differences between proximal and distal CRC. PLAGL2 and POFUT1, which have the highest correlation with tumor location, may serve as biomarkers and therapeutic targets for the precise diagnosis and treatment of CRC in the future. | 31638246 |
| 2020-02-22 11:57:00 | High POFUT1 expression was also associated with Notch signaling enrichment and with decreased goblet cells differentiation. In-depth molecular characterization of colorectal adenomas revealed POFUT1 and Notch signaling as potential drivers of tumor progression. | 31411736 |
| 2020-01-11 11:36:00 | Our team identified for the first time a bidirectional promoter pair oncogene, PLAGL2-POFUT1, in colorectal cancer (CRC). | 31279780 |
| 2019-12-14 12:36:00 | we revealed that poFUT1 was increased in the secretory phase compared to the proliferative phase. Meanwhile, poFUT1 was expressed at lower levels in the uterine endometrium of miscarriage patients than that in normal early pregnancies. Moreover, we provides novel evidence showing that poFUT1 controls the O-fucosylation and activation ofNotch1. | 31201143 |
| Type | IDs |
|---|---|
| Synonymous | DDD2, FUT12, O-FUT, O-Fuc-T, O-FucT-1, OFUCT1 |
| Gene |
UniProtKB-ID:
OFUT1_HUMAN
UniprotKB:
Q9H488
UniParc:
UPI000002B016,
UPI0000130C42
EMBL:
D80002,
BC000582,
AF375884,
AL121897,
CH471077,
AK291033
Ensembl:
ENSG00000101346
KO:
hsa:23509
|
| Nucleutide sequences |
EMBL-CDS:
EAW76385.1,
BAA11497.2,
AAH00582.1,
EAW76383.1,
BAF83722.1,
AAL09576.1,
EAW76384.1
Ensembl_TRS:
ENST00000375730,
ENST00000375749
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364882,
ENSP00000364902
RefSeq:
NP_056167.1,
NP_758436.1
|
| Others |
UniRef100:
UniRef100_Q9H488
UniRef90:
UniRef90_Q9H488
UniRef50:
UniRef50_Q9H488
UniGene:
Hs.472409
CCDS:
CCDS13199.1,
CCDS13198.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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