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235072 Sept7

235072

Sept7

septin 7

protein-coding

Mus musculus

基因描述

Type Description
Definition septin 7

研究结论

Date Results Publications
2019-05-25 10:54:00 This study revealed septin7 may potentially play a proapoptotic role in podocyte under diabetic conditions. 30361092
2017-08-19 12:35:00 SEPT7 regulates gross morphogenesis of the inner ear and maintains the size of the inner ear sensory epithelial area. It does not affect differentiation of hair cells and supporting cells. It exerts its effects at an early developmental stage of the inner ear. 27634570
2016-07-16 11:28:00 Sept7-deficient T cells failed to complete cytokinesis when prompted by pharmacological activation or cytokines. In contrast, cell division was not dependent on sept7 when cell-cell contacts, such as those with antigen-presenting cells, provided a niche. 26692174
2015-11-07 11:28:00 We identified stathmin as a key molecule aiding in septin-independent cytokinesis, demonstrated that stathmin supplementation is sufficient to override cytokinesis failure in SEPT7-null fibroblasts 25122120
2014-05-03 10:47:00 Sept7 provides a physical scaffold for HDAC6 to achieve efficient microtubule deacetylation, thereby negatively regulating microtubule stability to an optimal level for neuritogenesis. 24113571

名称对应

Type IDs
Synonymous Cdc10, E430034N22
Gene
UniProtKB-ID: SEPT7_MOUSE, E9Q1G8_MOUSE
UniprotKB: O55131, E9Q1G8
UniParc: UPI0000167E23, UPI0000027AD8
EMBL: AJ223784, AJ223787, AJ223782, AJ223783, CT025561, BC058587, AJ223788, AJ223786, AJ223794, AJ223790, AJ223789, AJ223793, AJ223785, AJ223792, AJ223791
Ensembl: ENSMUSG00000001833
KO: mmu:235072
Nucleutide sequences
EMBL-CDS: AAH58587.1, CAA11547.1
Ensembl_TRS: ENSMUST00000165594
Protein sequencees
Ensembl_PRO: ENSMUSP00000127641
RefSeq: NP_001346665.1, NP_001192296.1, XP_030100143.1, NP_001346666.1, XP_036010756.1, XP_006510253.1, NP_001346667.1, NP_033989.2
Others
UniRef100: UniRef100_O55131, UniRef100_E9Q1G8
UniRef90: UniRef90_Q16181, UniRef90_E9Q1G8
UniRef50: UniRef50_Q16181
UniGene: Mm.270259

全选

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