| Type | Description |
|---|---|
| Definition | retinol dehydrogenase 8 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 11:35:00 | a comprehensive analysis using RNA-seq identified important roles of the acute stress response in the degenerating retina of Abca4-/-Rdh8-/- mice that are predisposed to retinal degeneration under light stress. | 27315541 |
| 2012-09-29 11:03:00 | Findings are consistent with localization of RDH8 to the outer segment where it provides most of the activity needed to reduce all-trans-retinal generated by the light response. | 22621924 |
| 2010-01-21 00:00:00 | mice lacking both the ATP-binding cassette transporter 4 (Abca4) and enzyme retinol dehydrogenase 8 (Rdh8), proteins critical for all-trans-retinal clearance from photoreceptors, developed severe RPE/photoreceptor dystrophy at an early age | 18658157 |
| 2010-01-21 00:00:00 | prRDH is an enzyme that catalyzes reduction of all-trans-retinal in the rod outer segment, most noticeably at higher light intensities and prolonged illumination, but is not an essential enzyme of the retinoid cycle | 15755727 |
| Type | IDs |
|---|---|
| Synonymous | Gm182, prRDH |
| Gene |
UniProtKB-ID:
D3Z6W3_MOUSE
UniprotKB:
D3Z6W3
UniParc:
UPI00001E4495
EMBL:
AC166365
Ensembl:
ENSMUSG00000053773
KO:
mmu:235033
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000066387
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000067662
RefSeq:
NP_001025461.1
|
| Others |
UniRef100:
UniRef100_D3Z6W3
UniRef90:
UniRef90_D3Z6W3
UniRef50:
UniRef50_Q9NYR8
UniGene:
Mm.297661
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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