| Type | Description |
|---|---|
| Definition | zinc finger FYVE-type containing 26 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 12:11:00 | ZFYVE26 and SPG11 are differently involved in autophagy and endocytosis. | 30081747 |
| 2019-03-16 10:49:00 | Here, we have generated induced pluripotent stem cells (iPSCs) from patients with two autosomal recessive forms of hereditary spastic paraplegia (HSP) , SPG15 and SPG48, which are caused by mutations in the ZFYVE26 and AP5Z1 genes encoding proteins in the same complex, the spastizin and AP5Z1 proteins, respectively. | 29726929 |
| 2017-12-16 10:25:00 | Our protocol showed high specificity and sensitivity for homozygosity detection and facilitated the identification of novel mutations in GAN, GBA2, and ZFYVE26 in four families affected by hereditary spastic paraplegia or Charcot-Marie-Tooth disease | 26492578 |
| 2015-07-25 11:10:00 | spastizin and spatacsin were essential components for the initiation of lysosomal tubulation. Together, these results link dysfunction of the autophagy/lysosomal biogenesis machinery to neurodegeneration. | 25365221 |
| 2014-11-22 10:06:00 | ZFYVE26 is a key determinant of autophagosome maturation | 24284334 |
| Type | IDs |
|---|---|
| Synonymous | FYVE-CENT, SPG15 |
| Gene |
UniProtKB-ID:
ZFY26_HUMAN
UniprotKB:
Q68DK2
UniParc:
UPI0000EE32DF,
UPI0001D147A3,
UPI0000EE32F7,
UPI00001C1006,
UPI0000EE32F9
EMBL:
AL049779,
AK304428,
AB425197,
AK128496,
BC008927,
AB002319,
CR749365,
BX538025,
CH471061,
BX648683,
BC033235,
AL121595,
CR749276,
BX537886
Ensembl:
ENSG00000072121
KO:
hsa:23503
|
| Nucleutide sequences |
EMBL-CDS:
CAD97971.1,
BAA20779.1,
AAH33235.2,
BAG65255.1,
CAH10379.1,
AAH08927.2,
BAG11658.1,
CAH18218.1,
BAC87467.1,
EAW80954.1,
CAD97882.1,
CAH18131.1
Ensembl_TRS:
ENST00000347230
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000251119
RefSeq:
XP_016876614.1,
XP_011534911.1,
XP_016876613.1,
NP_056161.2,
XP_016876617.1,
XP_016876616.1,
XP_016876615.1
|
| Others |
UniRef100:
UniRef100_Q68DK2
UniRef90:
UniRef90_Q68DK2
UniRef50:
UniRef50_Q68DK2
UniGene:
Hs.98041
CCDS:
CCDS9788.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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