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23491 CES3

23491

CES3

carboxylesterase 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition carboxylesterase 3

研究结论

Date Results Publications
2012-11-17 11:11:00 This study provides the first evidence of functional compensation whereby increased expression of CES3 restores intracellular cholesteryl ester hydrolytic activity and free cholesterol efflux in CES1-deficient cells. 22700792
2011-03-05 11:10:00 Studies indicate that CES3 mRNA isoform expression in several tissues, particularly in colon, trachea and in brain. 20422440
2010-09-15 22:06:00 Observational study of gene-disease association. (HuGE Navigator) 20529763
2010-02-22 12:11:00 CES3 seems to have a lower catalytic efficiency than the other two CESs for selected substrates. 19508181
2010-01-21 00:00:00 pharmacogenomic characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes 18794728

名称对应

Type IDs
Synonymous ES31
Gene
UniProtKB-ID: EST3_HUMAN, A0A0C4DFY7_HUMAN
UniprotKB: Q6UWW8, A0A0C4DFY7
UniParc: UPI000013E5D3, UPI0000047824, UPI00001A947A
EMBL: EU595874, BC053670, AC009084, AK025389, AY358609, CH471092
Ensembl: ENSG00000172828
KO: hsa:23491
Nucleutide sequences
EMBL-CDS: AAH53670.1, EAW83060.1, AAQ88972.1, BAB15123.1, ACD11491.1, EAW83062.1
Gene_ORFName: UNQ869/PRO1887, hCG_1775398
Ensembl_TRS: ENST00000303334, ENST00000543856, ENST00000394037
Protein sequencees
Ensembl_PRO: ENSP00000445559, ENSP00000304782, ENSP00000377602
RefSeq: NP_001172105.1, NP_079198.2, NP_001172106.1
Others
UniRef100: UniRef100_A0A0C4DFY7, UniRef100_Q6UWW8
UniRef90: UniRef90_Q6UWW8
UniRef50: UniRef50_Q6UWW8
UniGene: Hs.268700
CCDS: CCDS10826.1, CCDS54023.1

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Indiana University School of Medicine

3
2

Biogen Inc., 250 Binney Street, Cambridge, Massachusetts 02142, USA.

1
3

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

1
4

Celera Genomics, 45 West Gude Drive, Rockville, MD 20850, USA. humangenome@celera.com

1
5

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA

1
热点人员
排名 研究人员 文献
1

Sonal P Sanghani

3
2

William F Bosron

3
3

Joao A Paulo

2
4

John Szpyt

2
5

Steven P Gygi

2
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