| Type | Description |
|---|---|
| Definition | spire type actin nucleation factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 11:48:00 | After injection of double-strand RNA against Spire 1 and 2 (Spire1+2 double-strand RNA), actin mesh levels were significantly decreased compared with that of control (negative). Conserved zinc-binding cysteines in the FYVE domain of Spire2 are crucial for proper localization in the oocyte cortex and cytoplasmic vesicles. The interaction between FMN2 and Spire2 proteins does not affect localization of Spire2. | 30557038 |
| 2017-11-25 13:18:00 | The authors determined crystal structures of MyoVa-globular tail domain bound either to the Spir-2 motif or to Rab11 and show that a Spir-2:MyoVa:Rab11 complex can form. | 27623148 |
| 2014-03-08 11:19:00 | We describe a novel locus, called Streptococcus pneumoniae infection resistance 2 (Spir2) on Chr4, which influences time to morbidity and the development of bacteraemia post-infection. | 23577770 |
| 2011-10-15 11:29:00 | Spire1 and Spire2 drive two critical steps of asymmetric oocyte division | 21620703 |
| 2011-03-26 12:11:00 | Spir-2 is found to be expressed as a single mRNA in the developing nervous system and intestine. In adult mouse it is expressed in epithelial cells of the digestive tract, in neuronal cells of the nervous system, and in testical spermatocytes. | 20723621 |
| Type | IDs |
|---|---|
| Synonymous | BC026502, Spir-2, Spir2 |
| Gene |
UniProtKB-ID:
SPIR2_MOUSE
UniprotKB:
Q8K1S6
UniParc:
UPI00000E6497,
UPI00000284FF
EMBL:
AJ459115,
BC026502,
BC049152
Ensembl:
ENSMUSG00000010154
KO:
mmu:234857
|
| Nucleutide sequences |
EMBL-CDS:
AAH26502.1,
CAD30509.1,
AAH49152.1
Ensembl_TRS:
ENSMUST00000010298,
ENSMUST00000212404
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000148710,
ENSMUSP00000010298
RefSeq:
NP_758491.1
|
| Others |
UniRef100:
UniRef100_Q8K1S6
UniRef90:
UniRef90_Q8K1S6
UniRef50:
UniRef50_Q8K1S6
UniGene:
Mm.150200
CCDS:
CCDS22754.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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