| Type | Description |
|---|---|
| Definition | phospholipase C, gamma 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:32:00 | data identify a novel Plcgamma2/Tmem178 axis as a modulator of inflammatory cytokine production by monocytes/macrophages. | 30879886 |
| 2020-07-11 11:37:00 | Mycobacterium tuberculosis induces activation of macrophages PLC-gamma2 to inhibit their mycobactericidal response. | 30317660 |
| 2020-04-04 11:04:00 | PLCG2 expression is restricted primarily to microglia and granule cells of the dentate gyrus and its genetic variant is protective against Alzheimer's disease. | 30711010 |
| 2017-12-16 10:31:00 | Syk-induced signals in bone marrow stromal cell lines are mediated by phospholipase C gamma1 (PLCgamma1) in osteogenesis and PLCgamma2 in adipogenesis. | 28786489 |
| 2016-11-05 10:20:00 | Results show that mice with the mutated Plcg2 gene were less prone to transformation into MALT lymphomas as a result of elevated Treg numbers, and decrease of pro-inflammatory cytokines. | 26966907 |
| Type | IDs |
|---|---|
| Synonymous | PLC-gamma-2, PLCgamma2, Plcg-2 |
| Gene |
UniProtKB-ID:
PLCG2_MOUSE
UniprotKB:
Q8CIH5
UniParc:
UPI0000027259
EMBL:
BC019654,
BC023877,
AK151039,
AK142173
Ensembl:
ENSMUSG00000034330
KO:
mmu:234779
|
| Nucleutide sequences |
EMBL-CDS:
BAE30056.1,
AAH23877.1,
BAE24959.1,
AAH19654.1
Ensembl_TRS:
ENSMUST00000081232
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000079991
RefSeq:
NP_758489.1
|
| Others |
UniRef100:
UniRef100_Q8CIH5
UniRef90:
UniRef90_Q8CIH5
UniRef50:
UniRef50_P16885
UniGene:
Mm.192699
CCDS:
CCDS22700.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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