Type | Description |
---|---|
Definition | ATM interactor |
Date | Results | Publications |
---|---|---|
2020-06-06 13:37:00 | Heterozygous Atmin deletion significantly increased tumor cell proliferation, tumor burden, and tumor grade in the LSL-KRasG12D; Trp53 F/F (KP) mouse model of lung adenocarcinoma, identifying ATMIN as a haploinsufficient tumor suppressor. ATMIN-deficient KP lung tumor cells showed increased survival in response to replication stress and consequently accumulated DNA damage. | 31481498 |
2019-09-21 10:04:00 | This work indicates a novel role for non-canonical Wnt/planar cell polarity signalling in Autosomal Recessive Polycystic Kidney Disease and suggests ATMIN as a modulator of PKHD1. | 30414501 |
2017-12-30 10:51:00 | ASCIZ/ATMIN is dispensable for ATM activation, and contradict the previously reported dependence of ATM on ASCIZ/ATMIN. | 28648892 |
2017-10-14 11:38:00 | oncogenic MYC expression, which is synthetic lethal with Dynll1 deletion in B-2 cells, did not further reduce B-1a cell numbers in Dynll1-defcient mice. we found that the ASCIZ-DYNLL1 axis was also required for the early-juvenile development of aggressive MYC-driven and p53-deficient B cell lymphomas. | 28922373 |
2017-08-05 11:38:00 | ATMIN, therefore, has multiple roles in different cell types, and its absence results in perturbed hematopoiesis, especially during stress conditions and aging. | 27581360 |
Type | IDs |
---|---|
Synonymous | Asciz, gpg6, mKIAA0431 |
Gene |
UniProtKB-ID:
ATMIN_MOUSE
UniprotKB:
Q6P9S1
UniParc:
UPI00015DEF3B
EMBL:
AK122281,
AK087334,
BC060631,
BC027752,
AC162858
Ensembl:
ENSMUSG00000047388
KO:
mmu:234776
|
Nucleutide sequences |
EMBL-CDS:
AAH60631.1,
BAC39849.1,
BAC65563.1,
AAH27752.1
Ensembl_TRS:
ENSMUST00000109099
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104727
RefSeq:
XP_006530991.1,
XP_006530992.1,
NP_808368.3,
XP_006530990.1
|
Others |
UniRef100:
UniRef100_Q6P9S1
UniRef90:
UniRef90_Q6P9S1
UniRef50:
UniRef50_O43313
UniGene:
Mm.259736
CCDS:
CCDS22694.2
|
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Refseq |
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