| Type | Description |
|---|---|
| Definition | quinolinate phosphoribosyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:44:00 | Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT. | 32716908 |
| 2019-02-09 12:00:00 | Hepatic QPRT thus likely served as a cellular factor that dampened productive hepatitis c virus replication. | 28724915 |
| 2018-12-22 10:45:00 | Our data suggest that QPRT may play an important role in the pathogenesis of autism spectrum disorders in Chr16p11.2 deletion carriers. | 30443311 |
| 2017-06-03 11:36:00 | WT1 knock-down gave a corresponding decrease in QPRT gene and protein expression. Chromatin-immunoprecipitation revealed WT1 binding to a conserved site in the first intron of the QPRT gene. | 27889611 |
| 2016-12-17 11:48:00 | The structural features, size distribution, heat aggregation and ITC studies of the full-length enzyme and the enzyme lacking helix alpha1 strongly suggest that human QPRT acts as a hexamer for cooperative reactant binding via three dimeric subunits and maintaining stability. | 26805589 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-90n, QPRTase |
| Gene |
UniProtKB-ID:
NADC_HUMAN,
V9HWJ5_HUMAN,
B4DDH4_HUMAN
UniprotKB:
Q15274,
V9HWJ5,
B4DDH4
UniParc:
UPI000012FC96,
UPI000013C78C,
UPI00017A6CF2
EMBL:
AK293195,
D78177,
BT007231,
KJ534923,
BC005060,
BC018910,
EU794638,
BC010033
Ensembl:
ENSG00000103485
KO:
hsa:23475
|
| Nucleutide sequences |
EMBL-CDS:
AAP35895.1,
BAA11242.1,
AAH18910.1,
AAH10033.1,
AAH05060.1,
AHW56563.1,
ACJ13692.1,
BAG56735.1
Ensembl_TRS:
ENST00000395384,
ENST00000449759
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000378782,
ENSP00000404873
RefSeq:
NP_055113.3,
XP_016878590.1,
NP_001305178.1,
XP_005255280.2,
NP_001305179.2
|
| Others |
UniRef100:
UniRef100_B4DDH4,
UniRef100_Q15274,
UniRef100_V9HWJ5
UniRef90:
UniRef90_B4DDH4,
UniRef90_Q15274
UniRef50:
UniRef50_A0A2I3HS03,
UniRef50_Q15274
UniGene:
Hs.513484
CCDS:
CCDS10651.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员