| Type | Description |
|---|---|
| Definition | ETHE1 persulfide dioxygenase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 13:56:00 | ETHE1 and MOCS1 deficiencies: Disruption of mitochondrial bioenergetics, dynamics, redox homeostasis and endoplasmic reticulum-mitochondria crosstalk in patient fibroblasts. | 31477743 |
| 2019-08-17 10:45:00 | The mitochondrial enzyme ETHE1 is a persulfide dioxygenase essential for cellular sulfide detoxification, and its deficiency causes the severe and complex inherited metabolic disorder ethylmalonic encephalopathy (EE). | 30391543 |
| 2017-11-11 12:00:00 | observations indicate the severe impact of ETHE1 deficiency on cellular physiology and redox state | 27074420 |
| 2017-06-24 11:32:00 | ETHE1 is a major enzyme regulating endogenous glutathione persulfide /GS-(S)n-H and that its activity is controlled by polysulfidation of the Cys247 residue. | 27742479 |
| 2016-01-23 10:43:00 | ETHE1 R163W/R163Q mutations are associated with Ethylmalonic encephalopathy. | 25198162 |
| Type | IDs |
|---|---|
| Synonymous | HSCO, YF13H12 |
| Gene |
UniProtKB-ID:
ETHE1_HUMAN,
A0A0S2Z5B3_HUMAN,
B2RCZ7_HUMAN,
A0A0S2Z580_HUMAN,
A0A0S2Z5N8_HUMAN
UniprotKB:
O95571,
A0A0S2Z5B3,
B2RCZ7,
A0A0S2Z580,
A0A0S2Z5N8
UniParc:
UPI000004ABFD,
UPI0000073C7C,
UPI000020256F,
UPI00004DDEEF
EMBL:
BC008250,
KU178567,
AK315346,
CH471126,
D83198,
AC018758,
KU178565,
KU178566
Ensembl:
ENSG00000105755
KO:
hsa:23474
|
| Nucleutide sequences |
EMBL-CDS:
BAA34595.2,
AAG09063.1,
AAH08250.1,
ALQ34023.1,
EAW57196.1,
BAG37744.1,
EAW57195.1,
EAW57197.1,
ALQ34024.1,
ALQ34025.1
Gene_ORFName:
hCG_1995670,
hCG_1995670
Ensembl_TRS:
ENST00000292147
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000292147
RefSeq:
NP_001307796.1,
NP_001307797.1,
NP_055112.2,
NP_001307798.1,
XP_005258744.1
|
| Others |
UniRef100:
UniRef100_O95571,
UniRef100_A0A0S2Z580,
UniRef100_A0A0S2Z5N8
UniRef90:
UniRef90_A0A0A0MV56,
UniRef90_A0A2Y9IGU9,
UniRef90_O95571
UniRef50:
UniRef50_A0A0A0MV56,
UniRef50_A0A2Y9IGU9,
UniRef50_O95571
UniGene:
Hs.7486
CCDS:
CCDS12622.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员