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234734 Aars

234734

Aars

alanyl-tRNA synthetase

protein-coding

Mus musculus

基因描述

Type Description
Definition alanyl-tRNA synthetase

研究结论

Date Results Publications
2021-01-23 13:01:00 Methyltransferase-like 21C (METTL21C) methylates alanine tRNA synthetase at Lys-943 in muscle tissue. 32611769
2018-11-24 11:21:00 results identify an amino-acid-accepting co-regulator of tRNA synthetase editing, ANKRD16, as a new layer of the machinery that is essential to the prevention of severe pathologies that arise from defects in editing 29769718
2015-05-02 11:04:00 the pathological consequences of diminished tRNA synthetase editing activity, and thus translational infidelity, are dependent on the cell type and the extent of editing disruption 25422440
2010-01-21 00:00:00 the mouse sticky mutation, which causes cerebellar Purkinje cell loss and ataxia, is a missense mutation in the editing domain of the alanyl-tRNA synthetase gene that compromises the proofreading activity of this enzyme during aminoacylation of tRNAs 16906134

名称对应

Type IDs
Synonymous AI316495, C76919, sti
Gene
UniProtKB-ID: SYAC_MOUSE, Q3UD67_MOUSE
UniprotKB: Q8BGQ7, Q3UD67
UniParc: UPI00005AC997, UPI00000EB9CC
EMBL: AK085725, BC033273, AK044451, AK150227
Ensembl: ENSMUSG00000031960
KO: mmu:234734
Nucleutide sequences
EMBL-CDS: BAC31927.1, AAH33273.1, BAC39520.1, BAE29394.1
Ensembl_TRS: ENSMUST00000034441
Protein sequencees
Ensembl_PRO: ENSMUSP00000034441
RefSeq: NP_666329.2, XP_006530985.1, XP_006530987.1
Others
UniRef100: UniRef100_Q8BGQ7, UniRef100_Q3UD67
UniRef90: UniRef90_P49588-2, UniRef90_A0A384D1D9
UniRef50: UniRef50_P49588, UniRef50_P49588-2
UniGene: Mm.24174, Mm.491269
CCDS: CCDS40478.1

全选

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