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23473 CAPN7

23473

CAPN7

calpain 7

protein-coding

Homo sapiens

基因描述

Type Description
Definition calpain 7

研究结论

Date Results Publications
2014-10-18 10:11:00 The proteolytic activity of CAPN7 is important for the acceleration of EGFR degradation via the endosomal sorting pathway. 24953135
2013-09-28 10:41:00 Data indicate that CAPN 7 promotes endometrial stromal cell (hESC) migration and invasion by increasing the activity of MMP-2 via an increased ratio of MMP-2 to TIMP-2. 23855590
2013-07-27 11:51:00 Mutational analysis of calpain-7 reveals the importance of not only the N-terminal microtubule-interacting and trafficking domains but also the C-terminal C2 domain-like domains for proteolytic activity. 23497113
2012-06-09 11:23:00 The detected enhancement of autolysis of mGFP-fused calpain-7 by coexpression with CHMP1B and observed further activation by additional coexpression of IST1 in HEK293T cells. 21616915
2011-01-01 11:14:00 Results demonstrate that human calpain 7 is proteolytically active, and imply that calpain 7 is activated by ESCRT-III-related protein IST1. 20849418

名称对应

Type IDs
Synonymous CALPAIN7, PALBH
Gene
UniProtKB-ID: CAN7_HUMAN, Q7Z479_HUMAN
UniprotKB: Q9Y6W3, Q7Z479
UniParc: UPI00001B675A, UPI0000038A6D
EMBL: BC056202, AB028639
Ensembl: ENSG00000131375
KO: hsa:23473
Nucleutide sequences
EMBL-CDS: BAA78730.1, AAH56202.1
Ensembl_TRS: ENST00000253693
Protein sequencees
Ensembl_PRO: ENSP00000253693
RefSeq: XP_011531859.1, NP_055111.1, NP_001363020.1, NP_001363018.1, XP_011531858.1, NP_001363015.1, NP_001363016.1, XP_011531857.1, NP_001363022.1, NP_001363019.1
Others
UniRef100: UniRef100_Q9Y6W3, UniRef100_Q7Z479
UniRef90: UniRef90_Q9Y6W3
UniRef50: UniRef50_Q9Y6W3
UniGene: Hs.595234
CCDS: CCDS2624.1

全选

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研究热度

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