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234515 Inpp4b

234515

Inpp4b

inositol polyphosphate-4-phosphatase, type II

protein-coding

Mus musculus

基因描述

Type Description
Definition inositol polyphosphate-4-phosphatase, type II

研究结论

Date Results Publications
2020-08-15 19:04:00 Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice. 32413098
2019-03-02 12:37:00 data show that INPP4B modulates AR activity in normal prostate and its loss contributes to the AR-dependent transcriptional profile in prostate cancer. 30228349
2017-03-11 11:08:00 Data provides evidence that INPP4B may play a role in regulating callosal axon formation by the formation of Satb2-positive pyramidal neurons and controlling axon polarization. 27109423
2016-04-23 10:23:00 Study provides evidence that INPP4B loss can promote follicular-like thyroid cancer progression and metastasis in the context of PTEN haploinsufficiency through the isoform-specific regulation of AKT signaling at the endosomes. 25883022
2016-04-23 10:23:00 Results provide evidence that INPP4B is a bona fide tumor suppressor whose function is particularly important in situations of PTEN deficiency. Biochemical data demonstrates that INPP4B directly dephosphorylates PtdIns(3,4,5)P3. 25883023

名称对应

Type IDs
Synonymous E130107I17Rik
Gene
UniProtKB-ID: INP4B_MOUSE, Q1A6V1_MOUSE, Q3URI3_MOUSE, E9PVM1_MOUSE, E9PVM3_MOUSE, Q1A6V0_MOUSE, Q1A6U9_MOUSE
UniprotKB: Q6P1Y8, Q1A6V1, Q3URI3, E9PVM1, E9PVM3, Q1A6V0, Q1A6U9
UniParc: UPI00002329D9, UPI00000253FA, UPI0000D7DE06, UPI00005AC07A, UPI0000D7DE04, UPI00000255E9, UPI0000D7DE05
EMBL: DQ296613, BC064813, DQ296611, AC115778, AK141502, DQ296612, AC122751, AC119279, AC121136, AC158353, AC113041, AC113085
Ensembl: ENSMUSG00000037940
KO: mmu:234515
Nucleutide sequences
EMBL-CDS: AAH64813.1, ABC33848.1, BAE24705.1, ABC33849.1, ABC33850.1
Ensembl_TRS: ENSMUST00000042529, ENSMUST00000213285, ENSMUST00000169116, ENSMUST00000215332, ENSMUST00000172031, ENSMUST00000217122, ENSMUST00000109852
Protein sequencees
Ensembl_PRO: ENSMUSP00000044466, ENSMUSP00000131947, ENSMUSP00000150520, ENSMUSP00000131324, ENSMUSP00000148972, ENSMUSP00000105478, ENSMUSP00000150541
RefSeq: XP_030099350.1, XP_036009846.1, XP_011246653.1, XP_017168218.1, XP_017168215.1, XP_036009847.1, XP_036009852.1, XP_036009845.1, NP_001019788.1, NP_001284525.1, XP_006530921.1, XP_036009851.1, XP_006530925.1, XP_017168217.1, XP_036009844.1, XP_006530924.1, XP_036009850.1, NP_001284522.1, XP_006530919.1, XP_036009849.1, XP_006530917.1, NP_001284520.1, XP_006530918.1, XP_036009848.1, XP_011246654.1, XP_006530926.1
Others
UniRef100: UniRef100_Q1A6V1, UniRef100_Q6P1Y8, UniRef100_E9PVM1, UniRef100_Q1A6V0, UniRef100_Q1A6U9, UniRef100_E9PVM3
UniRef90: UniRef90_Q9QWG5
UniRef50: UniRef50_Q9QWG5
UniGene: Mm.324468
CCDS: CCDS22446.1

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