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234407 Colgalt1

234407

Colgalt1

collagen beta(1-O)galactosyltransferase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition collagen beta(1-O)galactosyltransferase 1

研究结论

Date Results Publications
2020-06-20 10:13:00 GLT25D1 catalyzes galactosylation of Hyl throughout the type I collagen molecule and that this modification may regulate maturation of collagen cross-linking, fibrillogenesis, and mineralization 31726007
2020-02-29 11:37:00 Results demonstrate that Glt25d1 knockout results in embryonic lethality and down-regulation of Glt25d1 may inhibit collagen secretion during liver fibrogenesis. 31759980
2020-02-22 12:19:00 Colgalt1 mutant could serve as a model of a human connective tissue disorder and/or congenital muscular dystrophy or myopathy. 31101663
2019-01-12 12:06:00 The downregulation of Glt25d1 deteriorated CCl4induced liver injury in mice, which may involve triggering inflammatory responses, apoptosis and TGFbeta1/Smad2 signaling pathway activation. 30132521

名称对应

Type IDs
Synonymous 2810024B22Rik, Glt25d1
Gene
UniProtKB-ID: GT251_MOUSE
UniprotKB: Q8K297
UniParc: UPI0000193EEA
EMBL: AK035788, BC056951, BC032165
Ensembl: ENSMUSG00000034807
KO: mmu:234407
Nucleutide sequences
EMBL-CDS: BAE43293.1, AAH32165.1, AAH56951.1
Ensembl_TRS: ENSMUST00000047903
Protein sequencees
Ensembl_PRO: ENSMUSP00000047923
RefSeq: NP_001351372.1, NP_666323.2
Others
UniRef100: UniRef100_Q8K297
UniRef90: UniRef90_Q8NBJ5
UniRef50: UniRef50_Q8NBJ5
UniGene: Mm.273836, Mm.334606
CCDS: CCDS22401.1

全选

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