| Type | Description |
|---|---|
| Definition | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 10:57:00 | CSGalNAcT1 plays important roles in connective tissue organization and following intramembranous ossification of the craniofacial skeleton. | 30459452 |
| 2019-06-29 11:08:00 | Here, we show that initiation of ocular dominance plasticity was impaired with reduced CS, using mice lacking a key CS-synthesizing enzyme, CSGalNAcT1. Two-photon in vivo imaging showed a weaker visual response of PV-cells with reduced CS compared to wild-type mice. Plasticity onset was restored by a homeoprotein Otx2, which binds the major CS-proteoglycan aggrecan and promotes its further expression. | 28974755 |
| 2018-07-28 10:47:00 | CSGalNAcT1 is important for plasticity, probably due to regulation of chondroitin sulfate-dependent perineuronal nets. | 28982363 |
| 2018-02-10 10:42:00 | propose that both t1 and t2 are necessary for CS synthesis and normal chondrocyte differentiation but are not sufficient for all CS synthesis in cartilage | 29287114 |
| 2011-04-16 12:08:00 | CSGalNAcT-1 is necessary for normal levels of endochondral ossification, and the decrease in CS amount in the growth plate by its absence causes a rapid catabolism of aggrecan. | 21148564 |
| Type | IDs |
|---|---|
| Synonymous | 4732435N03Rik, CSGalNAcT-1 |
| Gene |
UniProtKB-ID:
CGAT1_MOUSE
UniprotKB:
Q8BJQ9
UniParc:
UPI00000EB685
EMBL:
AK080687,
AK144089,
AK133567,
BC089162,
AK049770,
BC026599,
AK033522,
AK028688
Ensembl:
ENSMUSG00000036356
KO:
mmu:234356
|
| Nucleutide sequences |
EMBL-CDS:
BAC26066.1,
BAE25692.1,
BAE21729.1,
BAC37982.1,
AAH26599.1,
BAC33912.1,
BAC28340.1,
AAH89162.1
Ensembl_TRS:
ENSMUST00000130214,
ENSMUST00000078350
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000077459,
ENSMUSP00000119817
RefSeq:
NP_001239552.1,
XP_006509693.1,
XP_006509690.1,
XP_006509689.1,
XP_006509691.1,
XP_011240592.1,
XP_006509692.1,
NP_001351185.1,
NP_766341.4
|
| Others |
UniRef100:
UniRef100_Q8BJQ9
UniRef90:
UniRef90_Q8BJQ9
UniRef50:
UniRef50_Q8BJQ9
UniGene:
Mm.334569,
Mm.489712
CCDS:
CCDS22341.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员