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23432 GPR161

23432

GPR161

G protein-coupled receptor 161

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein-coupled receptor 161

研究结论

Date Results Publications
2020-06-27 10:19:00 Authors describe a novel brain tumor predisposition syndrome that is caused by germline GPR161 mutations and characterized by MBSHH in infants. 31609649
2019-06-08 12:08:00 rare variants of GPR161 from Spina bifida infants and determination of their functional relevance in the Shh and Wnt signaling pathways 30256984
2019-06-01 10:17:00 Gpr161 restricts cerebellar granule cell progenitor production by preventing premature and sonic hedgehog-dependent pathway activity, highlighting the importance of basal pathway suppression in tumorigenesis 29386106
2018-06-02 10:42:00 Gpr161 is a critical factor in the basal suppression machinery of Shh signaling, neural tube morphogenesis and closure. (Review) 27731925
2017-12-02 11:32:00 Gpr161 is an A-kinase anchoring protein and the cAMP-sensing complex acts as cilium-compartmentalized signalosome 27357676

名称对应

Type IDs
Synonymous RE2
Gene
UniProtKB-ID: GP161_HUMAN, A0A0A0MQW8_HUMAN
UniprotKB: Q8N6U8, A0A0A0MQW8
UniParc: UPI0001914F6D, UPI0000140F93, UPI0002065201, UPI00000725FD, UPI0000EE3C9E, UPI000004E76E, UPI0002065200
EMBL: AK299634, AL033532, BC028163, CH471067, AK122656, AK298797, AK298850, AY275468, AF091890, AK056040
Ensembl: ENSG00000143147
KO: hsa:23432
Nucleutide sequences
EMBL-CDS: BAH12873.1, AAH28163.1, BAG51611.1, BAH12884.1, AAC61598.1, AAP32300.1, BAG53646.1, BAH13082.1, EAW90819.1
Gene_ORFName: hCG_42392
Ensembl_TRS: ENST00000539777, ENST00000367836, ENST00000367835, ENST00000367838, ENST00000546300, ENST00000537209, ENST00000271357
Protein sequencees
Ensembl_PRO: ENSP00000444348, ENSP00000437576, ENSP00000441039, ENSP00000356809, ENSP00000356810, ENSP00000356812, ENSP00000271357
RefSeq: NP_722561.1, XP_011507678.1, XP_005245112.1, XP_011507674.1, NP_001336562.1, NP_001336564.1, NP_001254543.1, NP_001254542.1, NP_001254540.1, NP_001254539.1, NP_001254538.1, NP_001368838.1, XP_006711314.1, NP_001336561.1, NP_001336563.1, NP_001254541.1, NP_001362813.1, NP_001362814.1, XP_011507675.1, XP_006711316.2, XP_011507673.1, NP_001362812.1
Others
UniRef100: UniRef100_Q8N6U8, UniRef100_A0A0A0MQW8
UniRef90: UniRef90_B2RPY5, UniRef90_Q8N6U8-6
UniRef50: UniRef50_B2RPY5
UniGene: Hs.271809
CCDS: CCDS58043.1, CCDS58042.1, CCDS58045.1, CCDS1268.1, CCDS58044.1

全选

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研究热度

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