| Type | Description |
|---|---|
| Definition | RING1 and YY1 binding protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:33:00 | Upregulated miR4115p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma. | 33537835 |
| 2020-05-09 11:32:00 | RYBP suppresses esophageal squamous cell carcinoma proliferation by downregulating CDC6 and CDC45, thus inhibiting the G1-S transition | 32209426 |
| 2020-02-08 11:25:00 | the up-regulated expression of miR-769-5p contributed to Hepatocellular carcinoma progression possibly by targeting RYBP. | 31545279 |
| 2019-11-09 10:23:00 | ETS1 up-regulates human RYBP expression at transcriptional level. ETS1 binds to RYBP promoter region through a multiple of conserved ETS1 binding sites in RYBP promoter region. RYBP is required for ETS1-induced human tumor cell growth inhibition. | 30638661 |
| 2019-07-13 12:24:00 | Mechanistic dissection further disclosed that RYBP directly binds to ubiquitin protein ligase E3A (UBE3A) to promote its ubiquitination and proteasomal degradation in an autoubiquitination-independent manner | 30040487 |
| Type | IDs |
|---|---|
| Synonymous | AAP1, APAP-1, DEDAF, YEAF1 |
| Gene |
UniProtKB-ID:
RYBP_HUMAN
UniprotKB:
Q8N488
UniParc:
UPI0000070725
EMBL:
AF227959,
AB029551,
BC014959,
AF179286,
AY228125,
BC036459
Ensembl:
ENSG00000163602
KO:
hsa:23429
|
| Nucleutide sequences |
EMBL-CDS:
AAO73587.1,
BAA89486.1,
AAH14959.1,
AAD51858.1,
AAK63197.1,
AAH36459.1
Ensembl_TRS:
ENST00000477973
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000419494
RefSeq:
NP_036366.3
|
| Others |
UniRef100:
UniRef100_Q8N488
UniRef90:
UniRef90_Q8N488
UniRef50:
UniRef50_Q8N488
UniGene:
Hs.7910
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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