| Type | Description |
|---|---|
| Definition | farnesyltransferase, CAAX box, beta |
| Date | Results | Publications |
|---|---|---|
| 2014-01-11 11:15:00 | The results of this study show that activation in Ras signaling cascade may be implicated in the METH-induced death signaling pathway in neuroblastoma SH-SY5Y cells. | 23643986 |
| 2013-01-26 10:21:00 | Data show that protein farnesyltransferase (FTase) specificity can be "tuned" using a small number of active site contacts that play essential roles in discriminating against non-substrates in the wild-type enzyme. | 22992747 |
| 2013-01-05 11:28:00 | The level of FTase mRNA expression in cancer tissues is much higher than in normal tissues. FTase may play an important role in the genesis and development of PLC and may be one of the markers for the metastatic activity gained by liver tumor cells. | 22882915 |
| 2010-01-21 00:00:00 | farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models. | 11751396 |
| 2009-12-02 21:41:00 | Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | 19841875 |
| Type | IDs |
|---|---|
| Synonymous | FPTB |
| Gene |
UniProtKB-ID:
FNTB_HUMAN,
A0A384MEJ5_HUMAN
UniprotKB:
P49356,
A0A384MEJ5
UniParc:
UPI0000111EF4,
UPI0000E01571
EMBL:
BC020232,
L10414,
AK315714,
L00635,
AL139022,
AL135745,
GQ901022,
AK303739,
CH471061
Ensembl:
ENSG00000257365
KO:
hsa:2342,
hsa:100529261
|
| Nucleutide sequences |
EMBL-CDS:
BAG64712.1,
BAG38073.1,
AAA35854.1,
AAA86286.1,
EAW80897.1,
AAH20232.1,
ADO22539.1
Ensembl_TRS:
ENST00000246166
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000246166
RefSeq:
NP_002019.1
|
| Others |
UniRef100:
UniRef100_P49356
UniRef90:
UniRef90_P49356
UniRef50:
UniRef50_P49356
UniGene:
Hs.325531
CCDS:
CCDS9769.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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