| Type | Description |
|---|---|
| Definition | sirtuin 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:29:00 | SIRT4 prevents excitotoxicity via modulating glutamate metabolism in glioma cells. | 32081049 |
| 2020-05-30 11:52:00 | suppresses hepatocellular carcinoma tumorigenesis by undermining mTOR signaling | 30552782 |
| 2020-05-16 10:47:00 | Results demonstrate that downregulation of SIRT4 in TAMs modulates the alternative activation of macrophages and promotes HCC development via the axis. | 31744516 |
| 2020-05-16 10:31:00 | SIRT4 was induced and cooperated with IDE to degrade PTEN. | 30649986 |
| 2020-04-11 10:09:00 | This study establishes SIRT4 as key anabolic factor that activates TORC1 signaling and regulates lipogenesis, autophagy, and cell proliferation. | 31685549 |
| Type | IDs |
|---|---|
| Synonymous | SIR2L4 |
| Gene |
UniProtKB-ID:
SIR4_HUMAN
UniprotKB:
Q9Y6E7
UniParc:
UPI0000071F11
EMBL:
AF083109,
AC003982,
BC109319,
BC109320
Ensembl:
ENSG00000089163
KO:
hsa:23409
|
| Nucleutide sequences |
EMBL-CDS:
AAB95634.1,
AAI09321.1,
AAD40852.1,
AAI09320.1
Ensembl_TRS:
ENST00000202967
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000202967
RefSeq:
XP_006719372.1,
NP_001372662.1,
NP_001372664.1,
NP_001372663.1,
NP_036372.1
|
| Others |
UniRef100:
UniRef100_Q9Y6E7
UniRef90:
UniRef90_Q9Y6E7
UniRef50:
UniRef50_Q9Y6E7
UniGene:
Hs.50861
CCDS:
CCDS9194.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员