| Type | Description |
|---|---|
| Definition | sirtuin 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 10:08:00 | there is the direct interaction between SIRT5 and 2-oxoglutarate dehydrogenase (OGDH), and desuccinylation of OGDH by SIRT5 inhibits the activity of OGDH complex. | 31247190 |
| 2020-04-25 10:54:00 | High SIRT5 expression is associated with clear cell renal cell carcinoma tumorigenesis. | 30703481 |
| 2020-02-15 10:31:00 | SIRT5-mediated protein desuccinylation played an important role in promoting the migration of hypoxic gastric cancer cells. | 31970975 |
| 2019-12-21 11:17:00 | SIRT5-induced deacetylation of LDHB triggers hyperactivation of autophagy, a key event in tumorigenesis. | 30443978 |
| 2019-11-09 10:52:00 | study thus uncovers an important role of SIRT5 in regulating cellular energy metabolism and AMPK activation in response to energy stress. | 30759120 |
| Type | IDs |
|---|---|
| Synonymous | SIR2L5 |
| Gene |
UniProtKB-ID:
SIR5_HUMAN,
A0A024R012_HUMAN
UniprotKB:
Q9NXA8,
A0A024R012
UniParc:
UPI00017A6F31,
UPI000006F092,
UPI0000073EB3,
UPI0001DD21BE
EMBL:
AK294162,
AK302467,
AF083110,
AL441883,
AM393414,
AK000355,
BC000126,
CH471087
Ensembl:
ENSG00000124523
KO:
hsa:23408
|
| Nucleutide sequences |
EMBL-CDS:
CAL38292.1,
BAG63757.1,
EAW55332.1,
AAH00126.1,
BAA91107.1,
BAG57485.1,
AAD40853.1,
EAW55333.1,
EAW55334.1,
EAW55336.1,
EAW55335.1
Gene_ORFName:
hCG_37419
Ensembl_TRS:
ENST00000397350,
ENST00000606117,
ENST00000359782,
ENST00000379262
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380509,
ENSP00000352830,
ENSP00000368564,
ENSP00000476228
RefSeq:
NP_001363734.1,
XP_024302156.1,
NP_001363741.1,
NP_001363737.1,
NP_001363736.1,
XP_011512746.1,
NP_001229756.1,
NP_001363730.1,
NP_001180196.1,
XP_016866113.1,
NP_001363728.1,
NP_036373.1,
NP_001363731.1,
NP_001363742.1,
NP_001363733.1,
XP_016866111.1,
NP_001363735.1,
NP_001363732.1,
NP_112534.1,
NP_001363744.1,
NP_001363729.1,
XP_016866109.1,
NP_001363740.1,
NP_001363743.1,
NP_001363727.1,
NP_001363738.1,
NP_001363739.1
|
| Others |
UniRef100:
UniRef100_Q9NXA8
UniRef90:
UniRef90_Q9NXA8
UniRef50:
UniRef50_Q9NXA8
UniGene:
Hs.567431,
Hs.594133
CCDS:
CCDS4527.1,
CCDS4526.1,
CCDS54966.1,
CCDS56398.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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