| Type | Description |
|---|---|
| Definition | coactosin like F-actin binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-20 10:47:00 | Study uncovers a novel tumor-suppressor role for CLP/Cotl1 and identify the downstream effectors interleukin 24 (IL-24)/PERP and IL-24/MAPK/ERK/TGF-beta. | 28925397 |
| 2018-03-10 10:54:00 | our combined results elucidated genetic and epigenetic silencing of miR-506-3p enhances COTL1 oncogene expression to foster NSCLC progression. | 27893417 |
| 2014-10-04 10:06:00 | The roles of CLP and FLAP in in cellular leukotriene biosynthesis, were studied. | 25034252 |
| 2014-09-20 10:59:00 | COTL1 regulates lamellipodia dynamics in part by protecting F-actin from cofilin-mediated disassembly. | 24454796 |
| 2014-05-24 10:39:00 | PAI-RBP1 and C1orf142 expression levels are higher in 95D (high metastatic potential) than in 95C (low metastatic potential) non-small lung cancer cells, whereas COTL1 expression level is lower in 95D when compared to 95C cells. | 22373659 |
| Type | IDs |
|---|---|
| Synonymous | CLP |
| Gene |
UniProtKB-ID:
COTL1_HUMAN,
A0A384MTY2_HUMAN
UniprotKB:
Q14019,
A0A384MTY2
UniParc:
UPI0000127CAD
EMBL:
BC042970,
L54057,
BC010884,
BC016702,
BC010039,
BC053682,
CH471114,
AK315675,
BT006968,
GQ900973
Ensembl:
ENSG00000103187
KO:
hsa:23406
|
| Nucleutide sequences |
EMBL-CDS:
AAH53682.1,
AAH16702.1,
BAG38040.1,
EAW95477.1,
EAW95476.1,
AAA88022.1,
AAH10884.1,
AAH10039.1,
AAH42970.1,
AAP35614.1,
ADO22490.1
Ensembl_TRS:
ENST00000262428
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262428
RefSeq:
NP_066972.1
|
| Others |
UniRef100:
UniRef100_Q14019
UniRef90:
UniRef90_Q14019
UniRef50:
UniRef50_Q14019
UniGene:
Hs.289092
CCDS:
CCDS10947.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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