FRAT2 - FRAT regulator of WNT signaling pathway 2-BMKCloudï½ç¾è¿å®¢äº

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23401 FRAT2

基因描述

Type	Description
Definition	FRAT regulator of WNT signaling pathway 2

研究结论

Date	Results	Publications
2010-09-15 22:06:00	Observational study of gene-disease association. (HuGE Navigator)	20613673
2010-01-21 00:00:00	FRAT-2 enhances glycogen synthase kinase 3 beta-mediated phosphorylation of a primed substrate to a greater extent than an unprimed substrate	15522877
2010-01-21 00:00:00	It suggests that activation of GSK-3 inhibits PP-2A through up-regulation of I(2)(PP-2A) with hnRNP A18-involved mechanism.	17433504

名称对应

Type	IDs
Synonymous	FRAT-2
Gene	UniProtKB-ID: FRAT2_HUMAN UniprotKB: O75474 UniParc: UPI00000704DD EMBL: BC020165, AF062739, AL355490, AB045118 Ensembl: ENSG00000181274 KO: hsa:23401
Nucleutide sequences	EMBL-CDS: BAB39165.1, AAC39786.1, AAH20165.1 Ensembl_TRS: ENST00000371019
Protein sequencees	Ensembl_PRO: ENSP00000360058 RefSeq: NP_036215.1
Others	UniRef100: UniRef100_O75474 UniRef90: UniRef90_O75474 UniRef50: UniRef50_O75474 UniGene: Hs.140720 CCDS: CCDS7456.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
26673895	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray KÄ±rlÄ± , Samir Karaca , Heinz JÃ¼rgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk GÃ¶rlich	2015-01-01	CHA1, KRR1, SRO9, STE50, RRP7, RNQ1, DCC1, GBP2, SAT4, RVS161, YCR016W, PWP2, SSK22, SOL2, PAT1, YCR087C-A, OCA4, MOB2, EPL1, BUD27, FRS2, LOC1, YFR016C, LSB3, RPL2A, PHO4, SAP155, IRC6, ENT4, PRP19, RIX7, YLL032C, FRA1, ISA1, SPA2, PUF3, RPL8B, NOC3, SSL1, SSK1, NSE1, RLP24, SDO1, ADE16, RPL15A, STU2, RPS0B, FRS1, BMT6, KIN2, HRT3, REX3, YLR108C, CFT2, MSL5, ACE2, STM1, YLR157C-A, APS1, CBF5, SWI6, SKG3, HCR1, PWP1, NOP56, BUR2, GPN3, DBP9, GCD7, SGD1, STE11, NMD4, RPS22B, ROM2, STP3, IKI3, REH1, AFG2, UTP21, ATG17, TUS1, MAG2, ATG23, RPS1A, FPR4, PDP3, CDC24, RBG1, FUN12, MTW1, PRP45, MAK16, ECM1, GPB2, VPS8, KIN3, CDC15, YAT1, WHI4
24412244	Charting the molecular links between driver and susceptibility genes in colorectal cancer. Biochem. Biophys. Res. Commun. Rodrigo Arroyo , Miquel Duran-Frigola , Clara Berenguer , Montserrat Soler-LÃ³pez , Patrick Aloy	2014-03-21	DLC1, ERBB2, AKT1, SMAD1, SMAD4, PTPN12, RASA1, SHC1, BCL10
23455922	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Nat. Methods Markku Varjosalo , Roberto Sacco , Alexey Stukalov , Audrey van Drogen , Melanie Planyavsky , Simon Hauri , Ruedi Aebersold , Keiryn L Bennett , Jacques Colinge , Matthias Gstaiger , Giulio Superti-Furga	2013-04-01	FRAT1, TRAP1, YAF2, AKAP9, G3BP1, TRIM28, CDK2, CDK3, CDK4, CDK5, PATJ, CDK6, CDK7, DCAF7, SRRM1, CDK9, CDKN1A, CDKN1B, STUB1, LOC400927-CSNK1E, CDKN1C, SAP18, BCAS2, CDKN2A, CDKN2B, CDKN2C, PCGF3, TUBB4B, PRMT5, CDIPT, SEC23B, STK25, PRDX4, CCT7, CCT4, CCT2, HEXIM1, IGF2BP3, IGF2BP2, CCT8, YME1L1, AHCYL1, SDCCAG3, TRAFD1, RNPS1, PRDX3, EBNA1BP2, GCN1, ILVBL, TLK2, WDR5, CDC37, WDR6, RASSF1, AKAP11, RPL35, PDCD10, TP53RK, ZNF618, KLHDC3, CKS1B, CKS2, DCD, ZC3H18, HEXIM2, CREBBP, FAM199X, CRY1, DYNLL2, PARP1, MAPK14, CSK, CSNK1A1, CSNK1D, CSNK1E, CSNK2A1, CSNK2A2, CSNK2B, C18orf25, GRK2, GRK3, VPS13B, DVL2, DYRK1A, EEF2, ELAVL1, EP300, EWSR1, ATAD3C, FASN, FAM83B, GPC4, MAPK15, FGFR4, FKBP5, DHX30, MAPRE1, CCT5, WDFY3
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
17433504	Activation of glycogen synthase kinase-3 inhibits protein phosphatase-2A and the underlying mechanisms. Neurobiol. Aging Gong-Ping Liu , Yao Zhang , Xiu-Qing Yao , Chang-E Zhang , Jiang Fang , Qun Wang , Jian-Zhi Wang	2008-09-01	FRAT2, INS
15522877	FRAT-2 preferentially increases glycogen synthase kinase 3 beta-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation. J Biol Chem William H Stoothoff , Jae-Hyeon Cho , Roy P McDonald , Gail V W Johnson	2005-01-07	-
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7
15164054	The DNA sequence and comparative analysis of human chromosome 10. Nature P Deloukas , M E Earthrowl , D V Grafham , M Rubenfield , L French , C A Steward , S K Sims , M C Jones , S Searle , C Scott , K Howe , S E Hunt , T D Andrews , J G R Gilbert , D Swarbreck , J L Ashurst , A Taylor , J Battles , C P Bird , R Ainscough , J P Almeida , R I S Ashwell , K D Ambrose , A K Babbage , C L Bagguley , J Bailey , R Banerjee , K Bates , H Beasley , S Bray-Allen , A J Brown , J Y Brown , D C Burford , W Burrill , J Burton , P Cahill , D Camire , N P Carter , J C Chapman , S Y Clark , G Clarke , C M Clee , S Clegg , N Corby , A Coulson , P Dhami , I Dutta , M Dunn , L Faulkner , A Frankish , J A Frankland , P Garner , J Garnett , S Gribble , C Griffiths , R Grocock , E Gustafson , S Hammond , J L Harley , E Hart , P D Heath , T P Ho , B Hopkins , J Horne , P J Howden , E Huckle , C Hynds , C Johnson , D Johnson , A Kana , M Kay , A M Kimberley , J K Kershaw , M Kokkinaki , G K Laird , S Lawlor , H M Lee , D A Leongamornlert , G Laird , C Lloyd , D M Lloyd , J Loveland , J Lovell , S McLaren , K E McLay , A McMurray , M Mashreghi-Mohammadi , L Matthews , S Milne , T Nickerson , M Nguyen , E Overton-Larty , S A Palmer , A V Pearce , A I Peck , S Pelan , B Phillimore , K Porter , C M Rice , A Rogosin , M T Ross , T Sarafidou , H K Sehra , R Shownkeen , C D Skuce , M Smith , L Standring , N Sycamore , J Tester , A Thorpe , W Torcasso , A Tracey , A Tromans , J Tsolas , M Wall , J Walsh , H Wang , K Weinstock , A P West , D L Willey , S L Whitehead , L Wilming , P W Wray , L Young , Y Chen , R C Lovering , N K Moschonas , R Siebert , K Fechtel , D Bentley , R Durbin , T Hubbard , L Doucette-Stamm , S Beck , D R Smith , J Rogers	2004-05-27	TLX1NB, ABI1, C10orf131, ZNF503-AS2, LOC100132418, FAM25BP, FAM25G, FRAT1, TIMM23, MTRNR2L7, HSPD1P17, MTRNR2L5, ERVK-16, TIMM23B, PPIF, ACTR1A, OPTN, ADARB2, NEBL, PITRM1, RPP30, RPP38, DPYSL4, TACC2, ERLIN1, LBX1, NRG3, YME1L1, ZMYND11, PRDX3, VAX1, C10orf10, AKR1C4, HOGA1, CHUK, SORCS1, C10orf71, ZNF511, C10orf90, BTBD16, ZNF488, ZFYVE27, COMTD1, FRA10AC1, ANKRD22, PDZD8, AGAP4, BORCS7, LYZL2, GSTO2, SFR1, CALHM3, CLRN3, ANAPC16, SFXN4, COL17A1, KLF6, MAP3K8, TRUB1, DYDC1, HECTD2, FGFBP3, CACUL1, ADRA2A, CTSLP8, CYP2C19, CYP2C18, CYP17A1, USP54, NKX2-3, SLC35G1, CFAP58, AKR1C1, C10orf91, PWWP2B, DMBT1, DNA2, TRDMT1, ECHS1, EGR2, ANTXRL, PAGE2, ERCC6, PLAC9, ZCCHC24, ENKUR, STOX1, C10orf35, CCNY, TBATA, OTUD1, ZNF438, MARCH8, C10orf25, ZNF485, REEP3, UCMA, C10orf111, FAM171A1
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-
12095675	Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2. Gene Sarah J Freemantle , Holly B Portland , Katherine Ewings , Florence Dmitrovsky , Keith DiPetrillo , Michael J Spinella , Ethan Dmitrovsky	2002-05-29	-

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